Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C121379> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- NCIT_C121379 IAO_0000115 "Human autologous T-lymphocytes transduced with a lentiviral vector encoding a T-cell receptor (TCR) specific for the cancer-testis antigens (CTAs) NY-ESO-1 and L antigen family member 1 (LAGE-1; Cancer/Testis Antigen 2; CTAG2; CT2), with potential antineoplastic activity. Following leukapheresis, isolation of lymphocytes, expansion ex vivo, transduction, and reintroduction into the patient, letetresgene autoleucel specifically target and bind to NY-ESO-1/LAGE-1-overexpressing tumor cells. This may result in a cytotoxic T-lymphocyte (CTL)-mediated elimination of NY-ESO-1/LAGE-1-positive cancer cells. NY-ESO-1 and LAGE-1, members of the cancer-testis antigen (CTA) family, are overexpressed on the surface of various tumor cell types." @default.
- NCIT_C121379 NCIT_A32 NCIT_C1909 @default.
- NCIT_C121379 NCIT_A7 NCIT_C104049 @default.
- NCIT_C121379 NCIT_A7 NCIT_C39286 @default.
- NCIT_C121379 NCIT_NHC0 "C121379" @default.
- NCIT_C121379 NCIT_P106 "Cell" @default.
- NCIT_C121379 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C121379 NCIT_P107 "Letetresgene Autoleucel" @default.
- NCIT_C121379 NCIT_P108 "Letetresgene Autoleucel" @default.
- NCIT_C121379 NCIT_P207 "C4055426" @default.
- NCIT_C121379 NCIT_P319 "B5ME4ZU4BS" @default.
- NCIT_C121379 NCIT_P322 "CTRP" @default.
- NCIT_C121379 NCIT_P322 "FDA" @default.
- NCIT_C121379 NCIT_P322 "GDC" @default.
- NCIT_C121379 NCIT_P329 "786186" @default.
- NCIT_C121379 NCIT_P330 "786186" @default.
- NCIT_C121379 NCIT_P375 "Autologous Anti-NY-ESO-1/LAGE-1 TCR-transduced c259 T Lymphocytes GSK3377794" @default.
- NCIT_C121379 NCIT_P375 "Letetresgene Autoleucel" @default.
- NCIT_C121379 NCIT_P399 "786186" @default.
- NCIT_C121379 NCIT_R124 NCIT_C17828 @default.
- NCIT_C121379 NCIT_R124 NCIT_C17930 @default.
- NCIT_C121379 NCIT_R124 NCIT_C17937 @default.
- NCIT_C121379 NCIT_R124 NCIT_C18839 @default.
- NCIT_C121379 NCIT_R124 NCIT_C21124 @default.
- NCIT_C121379 NCIT_R124 NCIT_C45548 @default.
- NCIT_C121379 NCIT_R125 NCIT_C17828 @default.
- NCIT_C121379 NCIT_R125 NCIT_C17937 @default.
- NCIT_C121379 NCIT_R125 NCIT_C18095 @default.
- NCIT_C121379 NCIT_R125 NCIT_C18839 @default.
- NCIT_C121379 NCIT_R125 NCIT_C19053 @default.
- NCIT_C121379 NCIT_R125 NCIT_C21124 @default.
- NCIT_C121379 NCIT_R125 NCIT_C26280 @default.
- NCIT_C121379 NCIT_R125 NCIT_C40833 @default.
- NCIT_C121379 NCIT_R125 NCIT_C40912 @default.
- NCIT_C121379 NCIT_R72 NCIT_C104083 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12219 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12476 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12508 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12535 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12542 @default.
- NCIT_C121379 NCIT_R72 NCIT_C12543 @default.
- NCIT_C121379 NCIT_R72 NCIT_C21599 @default.
- NCIT_C121379 NCIT_R72 NCIT_C32725 @default.
- NCIT_C121379 NCIT_R72 NCIT_C33061 @default.
- NCIT_C121379 NCIT_R72 NCIT_C38434 @default.
- NCIT_C121379 NCIT_R72 NCIT_C38439 @default.
- NCIT_C121379 NCIT_R72 NCIT_C39567 @default.
- NCIT_C121379 NCIT_R72 NCIT_C39568 @default.
- NCIT_C121379 normalizedInformationContent "100" @default.
- NCIT_C121379 referenceCount "1" @default.
- NCIT_C121379 hasExactSynonym "Autologous Anti-NY-ESO-1/LAGE-1 TCR-transduced c259 T Lymphocytes GSK3377794" @default.
- NCIT_C121379 hasExactSynonym "Autologous T-Cells Expressing Enhanced TCRs Specific for NY-ESO-1/LAGE-1a GSK3377794" @default.
- NCIT_C121379 hasExactSynonym "Genetically Engineered NY-ESO-1 Specific [c259] T Cells GSK3377794" @default.
- NCIT_C121379 hasExactSynonym "Genetically Engineered NY-ESO-1/LAGE-1 Specific (c259) T Cells GSK3377794" @default.
- NCIT_C121379 hasExactSynonym "LETETRESGENE AUTOLEUCEL" @default.
- NCIT_C121379 hasExactSynonym "Letetresgene Autoleucel" @default.
- NCIT_C121379 hasExactSynonym "NY-ESO-1c259 T Cells GSK3377794" @default.
- NCIT_C121379 inSubset NCIT_C116977 @default.
- NCIT_C121379 inSubset NCIT_C116978 @default.
- NCIT_C121379 inSubset NCIT_C128784 @default.
- NCIT_C121379 inSubset NCIT_C157711 @default.
- NCIT_C121379 inSubset NCIT_C157712 @default.
- NCIT_C121379 inSubset NCIT_C176424 @default.
- NCIT_C121379 inSubset NCIT_C177537 @default.
- NCIT_C121379 inSubset NCIT_C63923 @default.
- NCIT_C121379 type Class @default.
- NCIT_C121379 isDefinedBy ncit.owl @default.
- NCIT_C121379 label "Letetresgene Autoleucel" @default.
- NCIT_C121379 subClassOf NCIT_C121379 @default.
- NCIT_C121379 subClassOf NCIT_C129820 @default.
- NCIT_C121379 subClassOf NCIT_C129821 @default.
- NCIT_C121379 subClassOf NCIT_C129826 @default.
- NCIT_C121379 subClassOf NCIT_C138180 @default.
- NCIT_C121379 subClassOf NCIT_C142078 @default.
- NCIT_C121379 subClassOf NCIT_C154231 @default.
- NCIT_C121379 subClassOf NCIT_C1908 @default.
- NCIT_C121379 subClassOf NCIT_C1909 @default.
- NCIT_C121379 subClassOf NCIT_C1962 @default.
- NCIT_C121379 subClassOf NCIT_C274 @default.
- NCIT_C121379 subClassOf NCIT_C28681 @default.
- NCIT_C121379 subClassOf NCIT_C307 @default.
- NCIT_C121379 subClassOf NCIT_C308 @default.