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- NCIT_C121637 IAO_0000115 "A solution containing the polymer polihexanide, with potential antimicrobial, disinfectant and wound healing activities. Upon application to a wound, polihexanide strongly binds to the wound surface and exerts an antiseptic effect through the binding of the positively charged guanidine groups of polihexanide with the negatively charged phospholipids of the bacterial cell membrane. This compromises the stability of the bacterial cell membrane, which results in the leakage of cytoplasmic components and leads to bacterial cell death. In addition, polihexanide accelerates wound healing by promoting epithelial cell migration and proliferation." @default.
- NCIT_C121637 NCIT_NHC0 "C121637" @default.
- NCIT_C121637 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C121637 NCIT_P108 "Polihexanide Solution" @default.
- NCIT_C121637 NCIT_P207 "C4053774" @default.
- NCIT_C121637 NCIT_P329 "770448" @default.
- NCIT_C121637 NCIT_P330 "770448" @default.
- NCIT_C121637 NCIT_P399 "770448" @default.
- NCIT_C121637 normalizedInformationContent "100" @default.
- NCIT_C121637 referenceCount "1" @default.
- NCIT_C121637 hasExactSynonym "PHMB Solution" @default.
- NCIT_C121637 hasExactSynonym "Polihexanide Solution" @default.
- NCIT_C121637 hasExactSynonym "Polyhexamethylenebiguanide Solution" @default.
- NCIT_C121637 hasExactSynonym "Polyhexanide Solution" @default.
- NCIT_C121637 inSubset NCIT_C176424 @default.
- NCIT_C121637 type Class @default.
- NCIT_C121637 isDefinedBy ncit.owl @default.
- NCIT_C121637 label "Polihexanide Solution" @default.
- NCIT_C121637 subClassOf NCIT_C121637 @default.
- NCIT_C121637 subClassOf NCIT_C1908 @default.
- NCIT_C121637 subClassOf NCIT_C1909 @default.
- NCIT_C121637 subClassOf NCIT_C254 @default.