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- NCIT_C121829 IAO_0000115 "An inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, mivebresib binds to the acetyl-lysine binding site of BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors." @default.
- NCIT_C121829 NCIT_A32 NCIT_C1909 @default.
- NCIT_C121829 NCIT_NHC0 "C121829" @default.
- NCIT_C121829 NCIT_P106 "Organic Chemical" @default.
- NCIT_C121829 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C121829 NCIT_P107 "Mivebresib" @default.
- NCIT_C121829 NCIT_P108 "Mivebresib" @default.
- NCIT_C121829 NCIT_P207 "C4053689" @default.
- NCIT_C121829 NCIT_P210 "1445993-26-9" @default.
- NCIT_C121829 NCIT_P319 "VR86R11J7J" @default.
- NCIT_C121829 NCIT_P322 "CTRP" @default.
- NCIT_C121829 NCIT_P322 "FDA" @default.
- NCIT_C121829 NCIT_P322 "GDC" @default.
- NCIT_C121829 NCIT_P329 "773809" @default.
- NCIT_C121829 NCIT_P330 "773809" @default.
- NCIT_C121829 NCIT_P375 "Mivebresib" @default.
- NCIT_C121829 NCIT_P399 "773809" @default.
- NCIT_C121829 normalizedInformationContent "100" @default.
- NCIT_C121829 referenceCount "1" @default.
- NCIT_C121829 hasExactSynonym "ABBV-075" @default.
- NCIT_C121829 hasExactSynonym "Ethanesulfonamide, N-(4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo(2,3-C)pyridin-4-yl)phenyl)-" @default.
- NCIT_C121829 hasExactSynonym "MIVEBRESIB" @default.
- NCIT_C121829 hasExactSynonym "Mivebresib" @default.
- NCIT_C121829 inSubset NCIT_C116977 @default.
- NCIT_C121829 inSubset NCIT_C116978 @default.
- NCIT_C121829 inSubset NCIT_C128784 @default.
- NCIT_C121829 inSubset NCIT_C157711 @default.
- NCIT_C121829 inSubset NCIT_C157712 @default.
- NCIT_C121829 inSubset NCIT_C176424 @default.
- NCIT_C121829 inSubset NCIT_C177537 @default.
- NCIT_C121829 inSubset NCIT_C63923 @default.
- NCIT_C121829 type Class @default.
- NCIT_C121829 isDefinedBy ncit.owl @default.
- NCIT_C121829 label "Mivebresib" @default.
- NCIT_C121829 subClassOf NCIT_C121829 @default.
- NCIT_C121829 subClassOf NCIT_C128462 @default.
- NCIT_C121829 subClassOf NCIT_C129824 @default.
- NCIT_C121829 subClassOf NCIT_C1908 @default.
- NCIT_C121829 subClassOf NCIT_C1909 @default.
- NCIT_C121829 subClassOf NCIT_C2189 @default.
- NCIT_C121829 subClassOf NCIT_C274 @default.