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- NCIT_C122369 IAO_0000115 "Therapies that target the activity of DNA methyltransferases. Hypomethylating agents, including azacitidine and decitabine, have been used in the therapy of myelodysplastic syndrome and secondary acute myeloid leukemia. Although it is not curative, it can induce an improvement in hematopoiesis and lead to prolonged overall survival. Use of hypomethylating agents in the treatment of sickle cell anemia and other hemoglobin disorders can trigger the expression of fetal hemoglobin, leading to significant improvements in clinical symptoms." @default.
- NCIT_C122369 NCIT_NHC0 "C122369" @default.
- NCIT_C122369 NCIT_P106 "Therapeutic or Preventive Procedure" @default.
- NCIT_C122369 NCIT_P107 "Hypomethylation Therapy" @default.
- NCIT_C122369 NCIT_P108 "Hypomethylation Therapy" @default.
- NCIT_C122369 NCIT_P207 "C4054751" @default.
- NCIT_C122369 NCIT_P322 "CTRP" @default.
- NCIT_C122369 normalizedInformationContent "100" @default.
- NCIT_C122369 referenceCount "1" @default.
- NCIT_C122369 hasExactSynonym "Hypomethylating Agent-Based Therapy" @default.
- NCIT_C122369 hasExactSynonym "Hypomethylating Therapy" @default.
- NCIT_C122369 hasExactSynonym "Hypomethylation Therapy" @default.
- NCIT_C122369 inSubset NCIT_C116977 @default.
- NCIT_C122369 inSubset NCIT_C118169 @default.
- NCIT_C122369 type Class @default.
- NCIT_C122369 isDefinedBy ncit.owl @default.
- NCIT_C122369 label "Hypomethylation Therapy" @default.
- NCIT_C122369 subClassOf NCIT_C122369 @default.
- NCIT_C122369 subClassOf NCIT_C15632 @default.
- NCIT_C122369 subClassOf NCIT_C16203 @default.
- NCIT_C122369 subClassOf NCIT_C25218 @default.
- NCIT_C122369 subClassOf NCIT_C43431 @default.
- NCIT_C122369 subClassOf NCIT_C49236 @default.