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- NCIT_C122708 IAO_0000115 "A proprietary topical gel formulation containing an extract of curcumin, the polyphenol derived from the plant Curcuma longa, with potential anti-inflammatory, antioxidant, and wound healing activities. Upon topical administration to the affected areas, curcumin inhibits a variety of pro-inflammatory enzymes and reduces the production of certain pro-inflammatory mediators. Curcumin also blocks the formation of reactive oxygen species (ROS), neutralizes free radicals and prevents oxidative stress and DNA damage. In addition, curcumin inhibits phosphorylase kinase (PhK) in the skin, which prevents multiple PhK-mediated signal transduction pathways that are induced upon skin injury. This further prevents inflammation, promotes healing and reduces scar tissue formation. The proprietary curcumin-based gel also provides moisture to the skin and contains tetrahydropiperine (THP), which is derived from black pepper fruit and increases skin uptake of curcumin." @default.
- NCIT_C122708 NCIT_A7 NCIT_C17984 @default.
- NCIT_C122708 NCIT_A7 NCIT_C19705 @default.
- NCIT_C122708 NCIT_NHC0 "C122708" @default.
- NCIT_C122708 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C122708 NCIT_P107 "Curcumin-based Gel" @default.
- NCIT_C122708 NCIT_P108 "Curcumin-based Gel" @default.
- NCIT_C122708 NCIT_P207 "C4055175" @default.
- NCIT_C122708 NCIT_P322 "CTRP" @default.
- NCIT_C122708 NCIT_P329 "776115" @default.
- NCIT_C122708 NCIT_P330 "776115" @default.
- NCIT_C122708 NCIT_P399 "776115" @default.
- NCIT_C122708 normalizedInformationContent "100" @default.
- NCIT_C122708 referenceCount "1" @default.
- NCIT_C122708 hasExactSynonym "Curcumin Gel" @default.
- NCIT_C122708 hasExactSynonym "Curcumin-based Gel" @default.
- NCIT_C122708 hasExactSynonym "Psoria-Gold" @default.
- NCIT_C122708 hasExactSynonym "Topical Curcumin" @default.
- NCIT_C122708 inSubset NCIT_C116977 @default.
- NCIT_C122708 inSubset NCIT_C116978 @default.
- NCIT_C122708 inSubset NCIT_C176424 @default.
- NCIT_C122708 type Class @default.
- NCIT_C122708 isDefinedBy ncit.owl @default.
- NCIT_C122708 label "Curcumin-based Gel" @default.
- NCIT_C122708 subClassOf NCIT_C122708 @default.
- NCIT_C122708 subClassOf NCIT_C1323 @default.
- NCIT_C122708 subClassOf NCIT_C1908 @default.
- NCIT_C122708 subClassOf NCIT_C1909 @default.
- NCIT_C122708 subClassOf NCIT_C2198 @default.
- NCIT_C122708 subClassOf NCIT_C2356 @default.
- NCIT_C122708 subClassOf NCIT_C241 @default.
- NCIT_C122708 subClassOf NCIT_C257 @default.
- NCIT_C122708 subClassOf NCIT_C471 @default.
- NCIT_C122708 subClassOf NCIT_C78272 @default.