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- NCIT_C122834 IAO_0000115 "An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells." @default.
- NCIT_C122834 NCIT_A32 NCIT_C1909 @default.
- NCIT_C122834 NCIT_A7 NCIT_C38361 @default.
- NCIT_C122834 NCIT_NHC0 "C122834" @default.
- NCIT_C122834 NCIT_P106 "Organic Chemical" @default.
- NCIT_C122834 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C122834 NCIT_P107 "Selective Estrogen Receptor Degrader AZD9496" @default.
- NCIT_C122834 NCIT_P108 "Selective Estrogen Receptor Degrader AZD9496" @default.
- NCIT_C122834 NCIT_P207 "C4053676" @default.
- NCIT_C122834 NCIT_P210 "1639042-08-2" @default.
- NCIT_C122834 NCIT_P319 "DA9P7LN909" @default.
- NCIT_C122834 NCIT_P322 "CTRP" @default.
- NCIT_C122834 NCIT_P322 "FDA" @default.
- NCIT_C122834 NCIT_P322 "GDC" @default.
- NCIT_C122834 NCIT_P329 "764993" @default.
- NCIT_C122834 NCIT_P330 "764993" @default.
- NCIT_C122834 NCIT_P375 "Selective Estrogen Receptor Degrader AZD9496" @default.
- NCIT_C122834 NCIT_P399 "764993" @default.
- NCIT_C122834 normalizedInformationContent "100" @default.
- NCIT_C122834 referenceCount "1" @default.
- NCIT_C122834 hasExactSynonym "(E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid" @default.
- NCIT_C122834 hasExactSynonym "AZD 9496" @default.
- NCIT_C122834 hasExactSynonym "AZD-9496" @default.
- NCIT_C122834 hasExactSynonym "AZD9496" @default.
- NCIT_C122834 hasExactSynonym "SERD AZD9496" @default.
- NCIT_C122834 hasExactSynonym "Selective Estrogen Receptor Degrader AZD9496" @default.
- NCIT_C122834 inSubset NCIT_C116977 @default.
- NCIT_C122834 inSubset NCIT_C116978 @default.
- NCIT_C122834 inSubset NCIT_C128784 @default.
- NCIT_C122834 inSubset NCIT_C157711 @default.
- NCIT_C122834 inSubset NCIT_C157712 @default.
- NCIT_C122834 inSubset NCIT_C176424 @default.
- NCIT_C122834 inSubset NCIT_C177537 @default.
- NCIT_C122834 inSubset NCIT_C63923 @default.
- NCIT_C122834 type Class @default.
- NCIT_C122834 isDefinedBy ncit.owl @default.
- NCIT_C122834 label "Selective Estrogen Receptor Degrader AZD9496" @default.
- NCIT_C122834 subClassOf NCIT_C122834 @default.
- NCIT_C122834 subClassOf NCIT_C129818 @default.
- NCIT_C122834 subClassOf NCIT_C147908 @default.
- NCIT_C122834 subClassOf NCIT_C163758 @default.
- NCIT_C122834 subClassOf NCIT_C1908 @default.
- NCIT_C122834 subClassOf NCIT_C1909 @default.
- NCIT_C122834 subClassOf NCIT_C2116 @default.
- NCIT_C122834 subClassOf NCIT_C274 @default.
- NCIT_C122834 subClassOf NCIT_C481 @default.
- NCIT_C122834 subClassOf NCIT_C547 @default.