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- NCIT_C123380 IAO_0000115 "A fully human monoclonal antibody against CD123 (interleukin-3 receptor alpha chain) with potential antineoplastic activity. Anti-CD123 monoclonal antibody KHK2823 binds to and neutralizes CD123, which is upregulated on leukemic stem cells (LSC) found in myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). This agent may inhibit IL-3-dependent signaling and proliferation and may prevent the uncontrolled growth and differentiation of mutated LSC." @default.
- NCIT_C123380 NCIT_A32 NCIT_C1909 @default.
- NCIT_C123380 NCIT_NHC0 "C123380" @default.
- NCIT_C123380 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C123380 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C123380 NCIT_P108 "Anti-CD123 Monoclonal Antibody KHK2823" @default.
- NCIT_C123380 NCIT_P208 "CL474096" @default.
- NCIT_C123380 NCIT_P322 "GDC" @default.
- NCIT_C123380 NCIT_P329 "762775" @default.
- NCIT_C123380 NCIT_P330 "762775" @default.
- NCIT_C123380 NCIT_P375 "Anti-CD123 Monoclonal Antibody KHK2823" @default.
- NCIT_C123380 NCIT_P399 "762775" @default.
- NCIT_C123380 NCIT_R124 NCIT_C17710 @default.
- NCIT_C123380 NCIT_R124 NCIT_C17828 @default.
- NCIT_C123380 NCIT_R124 NCIT_C18219 @default.
- NCIT_C123380 NCIT_R124 NCIT_C19986 @default.
- NCIT_C123380 NCIT_R124 NCIT_C40474 @default.
- NCIT_C123380 normalizedInformationContent "100" @default.
- NCIT_C123380 referenceCount "1" @default.
- NCIT_C123380 hasExactSynonym "Anti-CD123 Monoclonal Antibody KHK2823" @default.
- NCIT_C123380 hasExactSynonym "KHK2823" @default.
- NCIT_C123380 inSubset NCIT_C128784 @default.
- NCIT_C123380 inSubset NCIT_C157711 @default.
- NCIT_C123380 inSubset NCIT_C157712 @default.
- NCIT_C123380 inSubset NCIT_C176424 @default.
- NCIT_C123380 inSubset NCIT_C177537 @default.
- NCIT_C123380 type Class @default.
- NCIT_C123380 isDefinedBy ncit.owl @default.
- NCIT_C123380 label "Anti-CD123 Monoclonal Antibody KHK2823" @default.
- NCIT_C123380 subClassOf NCIT_C123380 @default.
- NCIT_C123380 subClassOf NCIT_C129821 @default.
- NCIT_C123380 subClassOf NCIT_C129822 @default.
- NCIT_C123380 subClassOf NCIT_C1908 @default.
- NCIT_C123380 subClassOf NCIT_C1909 @default.
- NCIT_C123380 subClassOf NCIT_C201511 @default.
- NCIT_C123380 subClassOf NCIT_C20401 @default.
- NCIT_C123380 subClassOf NCIT_C274 @default.
- NCIT_C123380 subClassOf NCIT_C307 @default.
- NCIT_C123380 subClassOf NCIT_C308 @default.