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- NCIT_C123720 IAO_0000115 "Autologous tumor infiltrating lymphocytes (TILs) harvested directly from the infiltrate of a patient's tumor and treated with an inhibitor of the serine/threonine kinases Akt-1 and -2 (Akti-1/2) during ex vivo expansion, with potential antineoplastic activity. Upon reintroduction into the patient, the Akti-1/2-treated TILs recognize and kill cancer cells. Akt inhibition promotes the immunologic memory of the TILs and enhances their expansion, in vivo long-term persistence and antitumor activity." @default.
- NCIT_C123720 NCIT_NHC0 "C123720" @default.
- NCIT_C123720 NCIT_P106 "Cell" @default.
- NCIT_C123720 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C123720 NCIT_P107 "Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes" @default.
- NCIT_C123720 NCIT_P108 "Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes" @default.
- NCIT_C123720 NCIT_P207 "C4055481" @default.
- NCIT_C123720 NCIT_P322 "CTRP" @default.
- NCIT_C123720 NCIT_P329 "775186" @default.
- NCIT_C123720 NCIT_P330 "775186" @default.
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- NCIT_C123720 NCIT_R125 NCIT_C40912 @default.
- NCIT_C123720 NCIT_R72 NCIT_C104083 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12219 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12476 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12508 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12535 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12542 @default.
- NCIT_C123720 NCIT_R72 NCIT_C12543 @default.
- NCIT_C123720 NCIT_R72 NCIT_C21599 @default.
- NCIT_C123720 NCIT_R72 NCIT_C32725 @default.
- NCIT_C123720 NCIT_R72 NCIT_C33061 @default.
- NCIT_C123720 NCIT_R72 NCIT_C38434 @default.
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- NCIT_C123720 normalizedInformationContent "100" @default.
- NCIT_C123720 referenceCount "1" @default.
- NCIT_C123720 hasExactSynonym "AKTi-treated TIL" @default.
- NCIT_C123720 hasExactSynonym "AKTi-treated TILs" @default.
- NCIT_C123720 hasExactSynonym "Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes" @default.
- NCIT_C123720 hasExactSynonym "Akti-1/2-treated Tumor Infiltrating Lymphocytes" @default.
- NCIT_C123720 inSubset NCIT_C116977 @default.
- NCIT_C123720 inSubset NCIT_C116978 @default.
- NCIT_C123720 inSubset NCIT_C128784 @default.
- NCIT_C123720 inSubset NCIT_C176424 @default.
- NCIT_C123720 type Class @default.
- NCIT_C123720 isDefinedBy ncit.owl @default.
- NCIT_C123720 label "Akt-1/2 Inhibitor-treated Tumor Infiltrating Lymphocytes" @default.
- NCIT_C123720 subClassOf NCIT_C123720 @default.
- NCIT_C123720 subClassOf NCIT_C129820 @default.
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- NCIT_C123720 subClassOf NCIT_C142078 @default.
- NCIT_C123720 subClassOf NCIT_C1908 @default.
- NCIT_C123720 subClassOf NCIT_C1909 @default.
- NCIT_C123720 subClassOf NCIT_C201547 @default.
- NCIT_C123720 subClassOf NCIT_C274 @default.
- NCIT_C123720 subClassOf NCIT_C28681 @default.
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- NCIT_C123720 subClassOf NCIT_C308 @default.