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- NCIT_C123818 IAO_0000115 "A solution containing a high concentration of cromolyn sodium, with potential mast cell stabilizing, anti-tussive and anti-inflammatory activities. Upon inhalation of PA101 via a nebulizer, cromolyn blocks calcium ion influx into mast cells, thereby preventing the degranulation of mast cells in the lungs. This blocks the release of pro-inflammatory mediators from mast cells, such as histamine and slow-reacting substance of anaphylaxis (SRS-A), and prevents both bronchoconstriction and an inflammatory response. In indolent systemic mastocytosis (ISM), PA101 may be able to reduce the symptoms associated with this disease" @default.
- NCIT_C123818 NCIT_NHC0 "C123818" @default.
- NCIT_C123818 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C123818 NCIT_P108 "Cromolyn Sodium Inhalant PA101" @default.
- NCIT_C123818 NCIT_P208 "CL498212" @default.
- NCIT_C123818 NCIT_P329 "775466" @default.
- NCIT_C123818 NCIT_P330 "775466" @default.
- NCIT_C123818 NCIT_P399 "775466" @default.
- NCIT_C123818 normalizedInformationContent "100" @default.
- NCIT_C123818 referenceCount "1" @default.
- NCIT_C123818 hasExactSynonym "Cromolyn Sodium Inhalant PA101" @default.
- NCIT_C123818 hasExactSynonym "PA 101" @default.
- NCIT_C123818 hasExactSynonym "PA101" @default.
- NCIT_C123818 hasExactSynonym "Sodium Cromoglicate Inhalant PA10" @default.
- NCIT_C123818 inSubset NCIT_C176424 @default.
- NCIT_C123818 type Class @default.
- NCIT_C123818 isDefinedBy ncit.owl @default.
- NCIT_C123818 label "Cromolyn Sodium Inhalant PA101" @default.
- NCIT_C123818 subClassOf NCIT_C123818 @default.
- NCIT_C123818 subClassOf NCIT_C1908 @default.
- NCIT_C123818 subClassOf NCIT_C1909 @default.
- NCIT_C123818 subClassOf NCIT_C29712 @default.
- NCIT_C123818 subClassOf NCIT_C29714 @default.
- NCIT_C123818 subClassOf NCIT_C78273 @default.