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- NCIT_C1239 IAO_0000115 "An inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac. After oral administration, sulindac undergoes extensive biotransformation including irreversible oxidation to sulindac sulfone. Approximately, one half of an administered dose of sulindac is eliminated through the urine, mostly as the conjugated sulfone metabolite. (NCI04)" @default.
- NCIT_C1239 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1239 NCIT_A7 NCIT_C95469 @default.
- NCIT_C1239 NCIT_NHC0 "C1239" @default.
- NCIT_C1239 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1239 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1239 NCIT_P107 "Exisulind" @default.
- NCIT_C1239 NCIT_P108 "Exisulind" @default.
- NCIT_C1239 NCIT_P175 "719619" @default.
- NCIT_C1239 NCIT_P207 "C0075616" @default.
- NCIT_C1239 NCIT_P210 "59973-80-7" @default.
- NCIT_C1239 NCIT_P302 "Colonic adenomatous polyps in the inherited disease adenomatous polyposis coli, control and suppression" @default.
- NCIT_C1239 NCIT_P319 "K619IIG2R9" @default.
- NCIT_C1239 NCIT_P322 "CTRP" @default.
- NCIT_C1239 NCIT_P322 "FDA" @default.
- NCIT_C1239 NCIT_P322 "GDC" @default.
- NCIT_C1239 NCIT_P325 "A drug being studied in the treatment and prevention of cancer. It has been shown to cause apoptosis (cell death) in cells that are malignant (cancer) and in cells that may become cancer. It acts through a group of cellular enzymes called cGMP phosphodiesterases." @default.
- NCIT_C1239 NCIT_P329 "43057" @default.
- NCIT_C1239 NCIT_P330 "43057" @default.
- NCIT_C1239 NCIT_P350 "C20H17FO4S" @default.
- NCIT_C1239 NCIT_P366 "Sulindac_Sulfone" @default.
- NCIT_C1239 NCIT_P368 "CHEBI:64212" @default.
- NCIT_C1239 NCIT_P375 "Exisulind" @default.
- NCIT_C1239 NCIT_P399 "43057" @default.
- NCIT_C1239 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C1239 referenceCount "5" @default.
- NCIT_C1239 hasExactSynonym "(Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid" @default.
- NCIT_C1239 hasExactSynonym "1H-Indene-3-acetic Acid, 5-Fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene), (Z)" @default.
- NCIT_C1239 hasExactSynonym "Aptosyn" @default.
- NCIT_C1239 hasExactSynonym "EXISULIND" @default.
- NCIT_C1239 hasExactSynonym "Exisulind" @default.
- NCIT_C1239 hasExactSynonym "FGN-1" @default.
- NCIT_C1239 hasExactSynonym "Sulindac Sulfone" @default.
- NCIT_C1239 hasExactSynonym "Sulindac sulfone" @default.
- NCIT_C1239 hasExactSynonym "exisulind" @default.
- NCIT_C1239 inSubset NCIT_C116977 @default.
- NCIT_C1239 inSubset NCIT_C116978 @default.
- NCIT_C1239 inSubset NCIT_C128784 @default.
- NCIT_C1239 inSubset NCIT_C157711 @default.
- NCIT_C1239 inSubset NCIT_C157712 @default.
- NCIT_C1239 inSubset NCIT_C176424 @default.
- NCIT_C1239 inSubset NCIT_C177537 @default.
- NCIT_C1239 inSubset NCIT_C63923 @default.
- NCIT_C1239 type Class @default.
- NCIT_C1239 isDefinedBy ncit.owl @default.
- NCIT_C1239 label "Exisulind" @default.
- NCIT_C1239 subClassOf NCIT_C1239 @default.
- NCIT_C1239 subClassOf NCIT_C1908 @default.
- NCIT_C1239 subClassOf NCIT_C1909 @default.
- NCIT_C1239 subClassOf NCIT_C2127 @default.
- NCIT_C1239 subClassOf NCIT_C471 @default.
- NCIT_C1239 subClassOf NCIT_C744 @default.