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- NCIT_C124644 IAO_0000115 "A subset of therapeutic autologous T-lymphocytes that express a T-cell receptor (TCR) composed of one gamma chain and one delta chain, with potential immunomodulating and antineoplastic activities. Upon administration of the therapeutic gamma delta T-lymphocytes, these cells secrete interferon-gamma (IFN-g), and exert direct killing of tumor cells. In addition, these cells activate the immune system to exert a cytotoxic T-lymphocyte (CTL) response against tumor cells. Gamma delta T-lymphocytes play a key role in the activation of the immune system and do not require major histocompatibility complex (MHC)-mediated antigen presentation to exert their cytotoxic effect." @default.
- NCIT_C124644 NCIT_NHC0 "C124644" @default.
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- NCIT_C124644 NCIT_P108 "Therapeutic gamma delta T-lymphocytes" @default.
- NCIT_C124644 NCIT_P208 "CL502876" @default.
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- NCIT_C124644 hasExactSynonym "Therapeutic gamma delta T-lymphocytes" @default.
- NCIT_C124644 hasExactSynonym "gammadelta T Cells" @default.
- NCIT_C124644 hasExactSynonym "gd T Cells" @default.
- NCIT_C124644 inSubset NCIT_C128784 @default.
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- NCIT_C124644 type Class @default.
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- NCIT_C124644 label "Therapeutic gamma delta T-lymphocytes" @default.
- NCIT_C124644 subClassOf NCIT_C124644 @default.
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