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- NCIT_C124996 IAO_0000115 "A radioimmunoconjugate of tenatumomab, a murine monoclonal antibody targeting the tumor-associated antigen (TAA) tenascin-C (TNC), labeled with iodine I 131, with potential antineoplastic activity. The antibody moiety of iodine I 131 tenatumomab binds to TNC, thereby delivering a cytotoxic dose of iodine I 131 specifically to tumors expressing TNC. TNC, an extracellular matrix protein, is upregulated in a variety of tumor cell types; it plays a key role in invasion, tumor cell proliferation and immune evasion." @default.
- NCIT_C124996 NCIT_A32 NCIT_C1909 @default.
- NCIT_C124996 NCIT_NHC0 "C124996" @default.
- NCIT_C124996 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C124996 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C124996 NCIT_P108 "Iodine I 131 Tenatumomab" @default.
- NCIT_C124996 NCIT_P208 "CL503842" @default.
- NCIT_C124996 NCIT_P322 "GDC" @default.
- NCIT_C124996 NCIT_P329 "777273" @default.
- NCIT_C124996 NCIT_P330 "777273" @default.
- NCIT_C124996 NCIT_P375 "Iodine I 131 Tenatumomab" @default.
- NCIT_C124996 NCIT_P399 "777273" @default.
- NCIT_C124996 normalizedInformationContent "100" @default.
- NCIT_C124996 referenceCount "1" @default.
- NCIT_C124996 hasExactSynonym "131I-Tenatumomab" @default.
- NCIT_C124996 hasExactSynonym "Iodine I 131 Tenatumomab" @default.
- NCIT_C124996 inSubset NCIT_C128784 @default.
- NCIT_C124996 inSubset NCIT_C157711 @default.
- NCIT_C124996 inSubset NCIT_C157712 @default.
- NCIT_C124996 inSubset NCIT_C176424 @default.
- NCIT_C124996 inSubset NCIT_C177537 @default.
- NCIT_C124996 type Class @default.
- NCIT_C124996 isDefinedBy ncit.owl @default.
- NCIT_C124996 label "Iodine I 131 Tenatumomab" @default.
- NCIT_C124996 subClassOf NCIT_C124996 @default.
- NCIT_C124996 subClassOf NCIT_C129819 @default.
- NCIT_C124996 subClassOf NCIT_C1446 @default.
- NCIT_C124996 subClassOf NCIT_C1511 @default.
- NCIT_C124996 subClassOf NCIT_C1512 @default.
- NCIT_C124996 subClassOf NCIT_C1908 @default.
- NCIT_C124996 subClassOf NCIT_C1909 @default.
- NCIT_C124996 subClassOf NCIT_C2124 @default.
- NCIT_C124996 subClassOf NCIT_C274 @default.
- NCIT_C124996 subClassOf NCIT_C307 @default.
- NCIT_C124996 subClassOf NCIT_C308 @default.