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- NCIT_C126334 IAO_0000115 "A human monoclonal antibody against human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, U3-1784 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. FGFR4, a receptor tyrosine kinase overexpressed by certain tumor cell types, is involved in tumor cell proliferation, differentiation, angiogenesis, and survival." @default.
- NCIT_C126334 NCIT_A32 NCIT_C1909 @default.
- NCIT_C126334 NCIT_A7 NCIT_C25859 @default.
- NCIT_C126334 NCIT_NHC0 "C126334" @default.
- NCIT_C126334 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C126334 NCIT_P108 "Anti-FGFR4 Monoclonal Antibody U3-1784" @default.
- NCIT_C126334 NCIT_P208 "CL504900" @default.
- NCIT_C126334 NCIT_P322 "GDC" @default.
- NCIT_C126334 NCIT_P329 "779617" @default.
- NCIT_C126334 NCIT_P330 "779617" @default.
- NCIT_C126334 NCIT_P375 "Anti-FGFR4 Monoclonal Antibody U3-1784" @default.
- NCIT_C126334 NCIT_P399 "779617" @default.
- NCIT_C126334 NCIT_R124 NCIT_C17710 @default.
- NCIT_C126334 NCIT_R124 NCIT_C17828 @default.
- NCIT_C126334 NCIT_R124 NCIT_C18219 @default.
- NCIT_C126334 NCIT_R124 NCIT_C19986 @default.
- NCIT_C126334 NCIT_R124 NCIT_C40474 @default.
- NCIT_C126334 normalizedInformationContent "100" @default.
- NCIT_C126334 referenceCount "1" @default.
- NCIT_C126334 hasExactSynonym "Anti-FGFR4 Monoclonal Antibody U3-1784" @default.
- NCIT_C126334 hasExactSynonym "U3 1784" @default.
- NCIT_C126334 hasExactSynonym "U3-1784" @default.
- NCIT_C126334 inSubset NCIT_C128784 @default.
- NCIT_C126334 inSubset NCIT_C157711 @default.
- NCIT_C126334 inSubset NCIT_C157712 @default.
- NCIT_C126334 inSubset NCIT_C176424 @default.
- NCIT_C126334 inSubset NCIT_C177537 @default.
- NCIT_C126334 type Class @default.
- NCIT_C126334 isDefinedBy ncit.owl @default.
- NCIT_C126334 label "Anti-FGFR4 Monoclonal Antibody U3-1784" @default.
- NCIT_C126334 subClassOf NCIT_C126334 @default.
- NCIT_C126334 subClassOf NCIT_C129821 @default.
- NCIT_C126334 subClassOf NCIT_C129822 @default.
- NCIT_C126334 subClassOf NCIT_C133879 @default.
- NCIT_C126334 subClassOf NCIT_C163758 @default.
- NCIT_C126334 subClassOf NCIT_C164035 @default.
- NCIT_C126334 subClassOf NCIT_C1908 @default.
- NCIT_C126334 subClassOf NCIT_C1909 @default.
- NCIT_C126334 subClassOf NCIT_C20401 @default.
- NCIT_C126334 subClassOf NCIT_C274 @default.
- NCIT_C126334 subClassOf NCIT_C307 @default.
- NCIT_C126334 subClassOf NCIT_C308 @default.