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- NCIT_C127125 IAO_0000115 "A peptide-based cancer vaccine comprised of synthetic peptides derived from the cancer-testis antigen NY-ESO-1, preferentially expressed antigen in melanoma (PRAME), human melanoma antigen A3 (MAGE-A3) and the human Wilms tumor protein-1 (WT-1), with potential immunostimulating and antineoplastic activities. Upon administration, NY-ESO-1/PRAME/MAGE-A3/WT-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing NY-ESO-1, PRAME, MAGE-A3 and WT-1, resulting in tumor cell lysis. The NY-ESO-1, PRAME, MAGE-A3 and WT-1 peptides, tumor-associated antigens (TAAs) overexpressed in a variety of cancer cell types, play a key role in tumor cell proliferation." @default.
- NCIT_C127125 NCIT_NHC0 "C127125" @default.
- NCIT_C127125 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C127125 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C127125 NCIT_P108 "NY-ESO-1/PRAME/MAGE-A3/WT-1 Peptide Vaccine" @default.
- NCIT_C127125 NCIT_P208 "CL507915" @default.
- NCIT_C127125 NCIT_P329 "781018" @default.
- NCIT_C127125 NCIT_P330 "781018" @default.
- NCIT_C127125 NCIT_P399 "781018" @default.
- NCIT_C127125 NCIT_R124 NCIT_C17828 @default.
- NCIT_C127125 NCIT_R124 NCIT_C17930 @default.
- NCIT_C127125 NCIT_R124 NCIT_C17937 @default.
- NCIT_C127125 NCIT_R124 NCIT_C18839 @default.
- NCIT_C127125 NCIT_R124 NCIT_C21124 @default.
- NCIT_C127125 NCIT_R124 NCIT_C45548 @default.
- NCIT_C127125 normalizedInformationContent "100" @default.
- NCIT_C127125 referenceCount "1" @default.
- NCIT_C127125 hasExactSynonym "NPMW-peptide Vaccine" @default.
- NCIT_C127125 hasExactSynonym "NY-ESO-1/PRAME/MAGE-A3/WT-1 Peptide Vaccine" @default.
- NCIT_C127125 inSubset NCIT_C128784 @default.
- NCIT_C127125 inSubset NCIT_C176424 @default.
- NCIT_C127125 type Class @default.
- NCIT_C127125 isDefinedBy ncit.owl @default.
- NCIT_C127125 label "NY-ESO-1/PRAME/MAGE-A3/WT-1 Peptide Vaccine" @default.
- NCIT_C127125 subClassOf NCIT_C127125 @default.
- NCIT_C127125 subClassOf NCIT_C1752 @default.
- NCIT_C127125 subClassOf NCIT_C1908 @default.
- NCIT_C127125 subClassOf NCIT_C1909 @default.
- NCIT_C127125 subClassOf NCIT_C307 @default.
- NCIT_C127125 subClassOf NCIT_C308 @default.
- NCIT_C127125 subClassOf NCIT_C923 @default.