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- NCIT_C128277 IAO_0000115 "Activated caspase-3 (249 aa, ~29 kDa) is encoded by the human CASP3 gene. This protein plays a role in the promotion of apoptosis." @default.
- NCIT_C128277 NCIT_NHC0 "C128277" @default.
- NCIT_C128277 NCIT_P100 "600636" @default.
- NCIT_C128277 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C128277 NCIT_P106 "Enzyme" @default.
- NCIT_C128277 NCIT_P107 "Activated Caspase-3" @default.
- NCIT_C128277 NCIT_P108 "Activated Caspase-3" @default.
- NCIT_C128277 NCIT_P208 "CL508660" @default.
- NCIT_C128277 NCIT_P322 "CTRP" @default.
- NCIT_C128277 NCIT_P93 "P42574" @default.
- NCIT_C128277 NCIT_P98 "Active heterodimers between the small subunit of caspase-7 protease and the large subunit of caspase-3 and vice versa, also occur. (UniProt)" @default.
- NCIT_C128277 NCIT_P98 "Cleavage of caspase-3 by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits p17 and p12. Additional processing of caspase-3 propeptides is likely due to the autocatalytic activity of the activated protease. (UniProt)" @default.
- NCIT_C128277 NCIT_P98 "Denitrosylation of the active site thiol of caspase-3 is induced by the Fas-dependent apoptotic pathway and can also stimulate autocatalytic activity. (UniProt)" @default.
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- NCIT_C128277 normalizedInformationContent "100" @default.
- NCIT_C128277 referenceCount "1" @default.
- NCIT_C128277 hasExactSynonym "Activated CASP-3" @default.
- NCIT_C128277 hasExactSynonym "Activated CASP3" @default.
- NCIT_C128277 hasExactSynonym "Activated Caspase 3" @default.
- NCIT_C128277 hasExactSynonym "Activated Caspase-3" @default.
- NCIT_C128277 hasExactSynonym "Cleaved CASP-3" @default.
- NCIT_C128277 hasExactSynonym "Cleaved CASP3" @default.
- NCIT_C128277 hasExactSynonym "Cleaved Caspase 3" @default.
- NCIT_C128277 hasExactSynonym "Cleaved Caspase-3" @default.
- NCIT_C128277 inSubset NCIT_C116977 @default.
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- NCIT_C128277 type Class @default.
- NCIT_C128277 isDefinedBy ncit.owl @default.
- NCIT_C128277 label "Activated Caspase-3" @default.
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