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- NCIT_C128488 IAO_0000115 "A phospholipid-stabilized suspension composed of microbubbles containing the gas perfluorobutane (perflubutane, PFB) with an outer layer of hydrogenated egg phosphatidylserine (HEPS), which can be used as an ultrasound imaging contrast agent. Upon administration, the PFB microbubbles enhance echo differences between various tissues, which enhances the visualization of images during ultrasound. In particular, the PFB microbubbles seem to preferentially target the reticuloendothelial system (RES); they are taken up by macrophages in the spleen and liver (Kupffer cells), and are taken up in lymph nodes. This may aid in the detection and diagnosis of cancer and liver disease, and may improve imaging of the lymphatic and vascular systems. The microbubbles provide increased stability during ultrasound imaging." @default.
- NCIT_C128488 NCIT_NHC0 "C128488" @default.
- NCIT_C128488 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C128488 NCIT_P106 "Organic Chemical" @default.
- NCIT_C128488 NCIT_P107 "Perflubutane Microbubble" @default.
- NCIT_C128488 NCIT_P108 "Perflubutane Microbubble" @default.
- NCIT_C128488 NCIT_P207 "C3252337" @default.
- NCIT_C128488 NCIT_P322 "CTRP" @default.
- NCIT_C128488 normalizedInformationContent "100" @default.
- NCIT_C128488 referenceCount "1" @default.
- NCIT_C128488 hasExactSynonym "Microbubble Ultrasound Contrast Agent PFB" @default.
- NCIT_C128488 hasExactSynonym "PFB Microbubble" @default.
- NCIT_C128488 hasExactSynonym "Perflubutane Microbubble" @default.
- NCIT_C128488 hasExactSynonym "Perflubutane Microsphere" @default.
- NCIT_C128488 hasExactSynonym "Sonazoid" @default.
- NCIT_C128488 inSubset NCIT_C116977 @default.
- NCIT_C128488 inSubset NCIT_C116978 @default.
- NCIT_C128488 type Class @default.
- NCIT_C128488 isDefinedBy ncit.owl @default.
- NCIT_C128488 label "Perflubutane Microbubble" @default.
- NCIT_C128488 subClassOf NCIT_C128488 @default.
- NCIT_C128488 subClassOf NCIT_C1908 @default.
- NCIT_C128488 subClassOf NCIT_C1966 @default.
- NCIT_C128488 subClassOf NCIT_C390 @default.
- NCIT_C128488 subClassOf NCIT_C45678 @default.
- NCIT_C128488 subClassOf NCIT_C802 @default.