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- NCIT_C128557 IAO_0000115 "A multi-targeted agent with potential antineoplastic activity. Upon administration, NEV-801 appears to selectively inhibit topoisomerase (Topo) I and II, and activates hypoxia-inducible factor 1 (HIF-1) transcription and the expression of vascular endothelial growth factor (VEGF) mRNA. NEV-801 is also able to overcome multidrug resistance (MDR) 1-mediated resistance." @default.
- NCIT_C128557 NCIT_A32 NCIT_C1909 @default.
- NCIT_C128557 NCIT_A7 NCIT_C16516 @default.
- NCIT_C128557 NCIT_A7 NCIT_C18434 @default.
- NCIT_C128557 NCIT_NHC0 "C128557" @default.
- NCIT_C128557 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C128557 NCIT_P107 "Topoisomerase I/II Inhibitor NEV-801" @default.
- NCIT_C128557 NCIT_P108 "Topoisomerase I/II Inhibitor NEV-801" @default.
- NCIT_C128557 NCIT_P208 "CL507943" @default.
- NCIT_C128557 NCIT_P322 "CTRP" @default.
- NCIT_C128557 NCIT_P322 "GDC" @default.
- NCIT_C128557 NCIT_P329 "782337" @default.
- NCIT_C128557 NCIT_P330 "782337" @default.
- NCIT_C128557 NCIT_P375 "Topoisomerase I/II Inhibitor NEV-801" @default.
- NCIT_C128557 NCIT_P399 "782337" @default.
- NCIT_C128557 normalizedInformationContent "100" @default.
- NCIT_C128557 referenceCount "1" @default.
- NCIT_C128557 hasExactSynonym "NEV-801" @default.
- NCIT_C128557 hasExactSynonym "NEV801" @default.
- NCIT_C128557 hasExactSynonym "TopI/II NEV-801" @default.
- NCIT_C128557 hasExactSynonym "Topoisomerase I/II Inhibitor NEV-801" @default.
- NCIT_C128557 inSubset NCIT_C116977 @default.
- NCIT_C128557 inSubset NCIT_C116978 @default.
- NCIT_C128557 inSubset NCIT_C128784 @default.
- NCIT_C128557 inSubset NCIT_C157711 @default.
- NCIT_C128557 inSubset NCIT_C157712 @default.
- NCIT_C128557 inSubset NCIT_C176424 @default.
- NCIT_C128557 inSubset NCIT_C177537 @default.
- NCIT_C128557 type Class @default.
- NCIT_C128557 isDefinedBy ncit.owl @default.
- NCIT_C128557 label "Topoisomerase I/II Inhibitor NEV-801" @default.
- NCIT_C128557 subClassOf NCIT_C128557 @default.
- NCIT_C128557 subClassOf NCIT_C129824 @default.
- NCIT_C128557 subClassOf NCIT_C129825 @default.
- NCIT_C128557 subClassOf NCIT_C1748 @default.
- NCIT_C128557 subClassOf NCIT_C1908 @default.
- NCIT_C128557 subClassOf NCIT_C1909 @default.
- NCIT_C128557 subClassOf NCIT_C2189 @default.
- NCIT_C128557 subClassOf NCIT_C274 @default.
- NCIT_C128557 subClassOf NCIT_C471 @default.