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- NCIT_C128646 IAO_0000115 "A humanized monoclonal antibody fragment directed against the thrombin-binding site of dabigatran, that may be used as a specific reversal agent for dabigatran. Upon intravenous administration, idarucizumab binds to dabigatran and its acylglucuronide metabolites with a higher affinity than the binding affinity of dabigatran to thrombin, thereby neutralizing the anticoagulant effect of dabigatran." @default.
- NCIT_C128646 NCIT_NHC0 "C128646" @default.
- NCIT_C128646 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C128646 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C128646 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C128646 NCIT_P108 "Idarucizumab" @default.
- NCIT_C128646 NCIT_P207 "C3885063" @default.
- NCIT_C128646 NCIT_P210 "1362509-93-0" @default.
- NCIT_C128646 NCIT_P302 "treatment of patients treated with dabigatran (Pradaxa) when reversal of the anticoagulant effects of dabigatran is needed for emergency surgery/urgent procedures, or in life-threatening or uncontrolled bleeding" @default.
- NCIT_C128646 NCIT_P319 "97RWB5S1U6" @default.
- NCIT_C128646 NCIT_P322 "FDA" @default.
- NCIT_C128646 NCIT_R124 NCIT_C17710 @default.
- NCIT_C128646 NCIT_R124 NCIT_C17828 @default.
- NCIT_C128646 NCIT_R124 NCIT_C18219 @default.
- NCIT_C128646 NCIT_R124 NCIT_C19986 @default.
- NCIT_C128646 NCIT_R124 NCIT_C40474 @default.
- NCIT_C128646 normalizedInformationContent "100" @default.
- NCIT_C128646 referenceCount "1" @default.
- NCIT_C128646 hasExactSynonym "BI 655075" @default.
- NCIT_C128646 hasExactSynonym "IDARUCIZUMAB" @default.
- NCIT_C128646 hasExactSynonym "Idarucizumab" @default.
- NCIT_C128646 hasExactSynonym "Praxbind" @default.
- NCIT_C128646 inSubset NCIT_C63923 @default.
- NCIT_C128646 type Class @default.
- NCIT_C128646 isDefinedBy ncit.owl @default.
- NCIT_C128646 label "Idarucizumab" @default.
- NCIT_C128646 subClassOf NCIT_C128646 @default.
- NCIT_C128646 subClassOf NCIT_C1908 @default.
- NCIT_C128646 subClassOf NCIT_C1909 @default.
- NCIT_C128646 subClassOf NCIT_C20401 @default.
- NCIT_C128646 subClassOf NCIT_C307 @default.
- NCIT_C128646 subClassOf NCIT_C308 @default.
- NCIT_C128646 subClassOf NCIT_C78275 @default.