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- NCIT_C129596 IAO_0000115 "A therapeutic peptide vaccine containing the human telomerase reverse transcriptase catalytic subunit (hTERT)-derived universal cancer peptides 2 (UCP2) and 4 (UCP4), and combined with the immunoadjuvant Montanide ISA 51 VG, with potential immunostimulating and antineoplastic activities. Vaccination with the CD4-specific telomerase peptide vaccine UCPVax activates the immune system to mount a T-helper 1 (TH1) CD4-positive T-lymphocyte immune response against and ultimately killing telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation." @default.
- NCIT_C129596 NCIT_A32 NCIT_C1909 @default.
- NCIT_C129596 NCIT_NHC0 "C129596" @default.
- NCIT_C129596 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C129596 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C129596 NCIT_P108 "CD4-specific Telomerase Peptide Vaccine UCPVax" @default.
- NCIT_C129596 NCIT_P208 "CL512660" @default.
- NCIT_C129596 NCIT_P322 "GDC" @default.
- NCIT_C129596 NCIT_P329 "783988" @default.
- NCIT_C129596 NCIT_P330 "783988" @default.
- NCIT_C129596 NCIT_P375 "CD4-specific Telomerase Peptide Vaccine UCPVax" @default.
- NCIT_C129596 NCIT_P399 "783988" @default.
- NCIT_C129596 NCIT_R124 NCIT_C17828 @default.
- NCIT_C129596 NCIT_R124 NCIT_C17930 @default.
- NCIT_C129596 NCIT_R124 NCIT_C17937 @default.
- NCIT_C129596 NCIT_R124 NCIT_C18839 @default.
- NCIT_C129596 NCIT_R124 NCIT_C21124 @default.
- NCIT_C129596 NCIT_R124 NCIT_C45548 @default.
- NCIT_C129596 normalizedInformationContent "100" @default.
- NCIT_C129596 referenceCount "1" @default.
- NCIT_C129596 hasExactSynonym "CD4-specific Telomerase Peptide Vaccine UCPVax" @default.
- NCIT_C129596 hasExactSynonym "UCP2/UCP4 CD4-specific Telomerase Peptide Vaccine UCPVax" @default.
- NCIT_C129596 hasExactSynonym "UCPVax" @default.
- NCIT_C129596 inSubset NCIT_C128784 @default.
- NCIT_C129596 inSubset NCIT_C157711 @default.
- NCIT_C129596 inSubset NCIT_C157712 @default.
- NCIT_C129596 inSubset NCIT_C176424 @default.
- NCIT_C129596 inSubset NCIT_C177537 @default.
- NCIT_C129596 type Class @default.
- NCIT_C129596 isDefinedBy ncit.owl @default.
- NCIT_C129596 label "CD4-specific Telomerase Peptide Vaccine UCPVax" @default.
- NCIT_C129596 subClassOf NCIT_C129596 @default.
- NCIT_C129596 subClassOf NCIT_C1752 @default.
- NCIT_C129596 subClassOf NCIT_C1908 @default.
- NCIT_C129596 subClassOf NCIT_C1909 @default.
- NCIT_C129596 subClassOf NCIT_C307 @default.
- NCIT_C129596 subClassOf NCIT_C308 @default.
- NCIT_C129596 subClassOf NCIT_C923 @default.