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- NCIT_C129649 IAO_0000115 "An orally bioavailable, probiotic supplement containing the non-pathogenic microorganisms Bifidobacterium animalis and Lactobacillus rhamnosus subspecies lactis with potential immunomodulating, anti-diarrheal and mucosal protective activities. Upon oral ingestion, the naturally-occurring bacterial components in Bifidobacterium animalis/Lactobacillus rhamnosus subspecies lactis probiotic supplement may improve digestion and help to maintain adequate colonization of the gastrointestinal (GI) tract by modulating the composition of the normal microflora. They produce lactic acid, hydrogen peroxide and other substances during fermentation, thereby creating an acidic environment that is unfavorable for pathogens. During colonization in the GI tract, the bacteria may also form a protective intestinal barrier, which may prevent damage to the mucosal epithelium, maintains the integrity of the epithelial barrier from potential damage by toxins and certain chemicals, and reduces the potential for attachment of pathogens. This further protects against bacterial translocation and infection. In addition, this agent may reduce the secretion of pro-inflammatory cytokines and may potentiate natural and acquired immunity. Altogether, this may increase immunity, prevent GI mucosal damage, malabsorption, inflammation, and reduce diarrhea, such as diarrhea induced by inflammation and GI mucosa-damaging agents." @default.
- NCIT_C129649 NCIT_NHC0 "C129649" @default.
- NCIT_C129649 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C129649 NCIT_P108 "Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic Supplement" @default.
- NCIT_C129649 NCIT_P208 "CL512602" @default.
- NCIT_C129649 NCIT_P329 "784214" @default.
- NCIT_C129649 NCIT_P330 "784214" @default.
- NCIT_C129649 NCIT_P399 "784214" @default.
- NCIT_C129649 normalizedInformationContent "100" @default.
- NCIT_C129649 referenceCount "1" @default.
- NCIT_C129649 hasExactSynonym "BB-12/LGG" @default.
- NCIT_C129649 hasExactSynonym "Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic Supplement" @default.
- NCIT_C129649 hasExactSynonym "Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic" @default.
- NCIT_C129649 hasExactSynonym "Lactobacillus rhamnosus GG/ Bifidobacterium animalis subsp. lactis BB-12" @default.
- NCIT_C129649 hasExactSynonym "Lactobacillus rhamnosus/Bifidobacterium animalis subsp. lactis" @default.
- NCIT_C129649 hasExactSynonym "PROBIO-FIX INUM" @default.
- NCIT_C129649 inSubset NCIT_C176424 @default.
- NCIT_C129649 type Class @default.
- NCIT_C129649 isDefinedBy ncit.owl @default.
- NCIT_C129649 label "Bifidobacterium animalis/Lactobacillus rhamnosus Probiotic Supplement" @default.
- NCIT_C129649 subClassOf NCIT_C129649 @default.
- NCIT_C129649 subClassOf NCIT_C1505 @default.
- NCIT_C129649 subClassOf NCIT_C1908 @default.