Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1298> ?p ?o ?g. }
Showing items 1 to 43 of
43
with 100 items per page.
- NCIT_C1298 IAO_0000115 "A synthetic analog of fumagillin, an antibiotic isolated from the fungus Aspergillus fumigatus fresenius with antineoplastic activity. TNP-470 binds to and irreversibly inactivates methionine aminopeptidase-2 (MetAP2), resulting in endothelial cell cycle arrest late in the G1 phase and inhibition of tumor angiogenesis. This agent may also induce the p53 pathway, thereby stimulating the production of cyclin-dependent kinase inhibitor p21 and inhibiting angiogenesis. (NCI04)" @default.
- NCIT_C1298 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1298 NCIT_NHC0 "C1298" @default.
- NCIT_C1298 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1298 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1298 NCIT_P108 "O-Chloroacetylcarbamoylfumagillol" @default.
- NCIT_C1298 NCIT_P175 "642492" @default.
- NCIT_C1298 NCIT_P207 "C0081489" @default.
- NCIT_C1298 NCIT_P210 "129298-91-5" @default.
- NCIT_C1298 NCIT_P319 "X47GR46481" @default.
- NCIT_C1298 NCIT_P322 "FDA" @default.
- NCIT_C1298 NCIT_P322 "GDC" @default.
- NCIT_C1298 NCIT_P325 "A substance being studied in the treatment of cancer. It may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent." @default.
- NCIT_C1298 NCIT_P329 "41725" @default.
- NCIT_C1298 NCIT_P330 "41725" @default.
- NCIT_C1298 NCIT_P366 "TNP-470" @default.
- NCIT_C1298 NCIT_P375 "O-Chloroacetylcarbamoylfumagillol" @default.
- NCIT_C1298 NCIT_P399 "41725" @default.
- NCIT_C1298 normalizedInformationContent "100" @default.
- NCIT_C1298 referenceCount "1" @default.
- NCIT_C1298 hasExactSynonym "(3R,4S,5S,6R)-5-Methoxy-4- [(2R,3R)-2-methyl-3-(3-methyl-2-butenyl) -oxiranyl]-1-oxaspiro [2,5] oct-6-yl(chloroacetyl) Carbamate" @default.
- NCIT_C1298 hasExactSynonym "5-methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2,5)oct-6-yl(chloroacetyl) carbamate" @default.
- NCIT_C1298 hasExactSynonym "AGM-1470" @default.
- NCIT_C1298 hasExactSynonym "O-Chloroacetylcarbamoylfumagillol" @default.
- NCIT_C1298 hasExactSynonym "TNP-470" @default.
- NCIT_C1298 hasExactSynonym "[3R-[3alpha,4alpha(2R*,3R*),5beta,6beta]]-5-Methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl (chloroacetyl)carbamate" @default.
- NCIT_C1298 inSubset NCIT_C128784 @default.
- NCIT_C1298 inSubset NCIT_C157711 @default.
- NCIT_C1298 inSubset NCIT_C157712 @default.
- NCIT_C1298 inSubset NCIT_C176424 @default.
- NCIT_C1298 inSubset NCIT_C177537 @default.
- NCIT_C1298 inSubset NCIT_C63923 @default.
- NCIT_C1298 type Class @default.
- NCIT_C1298 isDefinedBy ncit.owl @default.
- NCIT_C1298 label "O-Chloroacetylcarbamoylfumagillol" @default.
- NCIT_C1298 subClassOf NCIT_C1298 @default.
- NCIT_C1298 subClassOf NCIT_C1742 @default.
- NCIT_C1298 subClassOf NCIT_C1908 @default.
- NCIT_C1298 subClassOf NCIT_C1909 @default.
- NCIT_C1298 subClassOf NCIT_C2143 @default.
- NCIT_C1298 subClassOf NCIT_C274 @default.
- NCIT_C1298 subClassOf NCIT_C471 @default.
- NCIT_C1298 subClassOf NCIT_C783 @default.