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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C129898> ?p ?o ?g. }

• NCIT_C129898 IAO_0000115 "Receptor tyrosine-protein kinase erbB-2 carboxyl terminal fragment is encoded by the human ERBB2 gene. This protein may be involved in tyrosine kinase activity and may be associated with increased cancer severity." @default.
• NCIT_C129898 NCIT_NHC0 "C129898" @default.
• NCIT_C129898 NCIT_P100 "164870" @default.
• NCIT_C129898 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
• NCIT_C129898 NCIT_P106 "Enzyme" @default.
• NCIT_C129898 NCIT_P107 "Receptor Tyrosine-Protein Kinase erbB-2 Carboxyl Terminal Fragment" @default.
• NCIT_C129898 NCIT_P108 "Receptor Tyrosine-Protein Kinase erbB-2 Carboxyl Terminal Fragment" @default.
• NCIT_C129898 NCIT_P208 "CL512925" @default.
• NCIT_C129898 NCIT_P322 "CTRP" @default.
• NCIT_C129898 NCIT_P93 "P04626" @default.
• NCIT_C129898 NCIT_P98 "Receptor tyrosine-protein kinase erbB-2 carboxyl terminal fragments (ERBB2 CTF) arise through at least two different mechanisms: proteolytic shedding of the full-length receptor tyrosine-protein kinase erbB-2 extracellular domain and translation of ERBB2 mRNA from internal initiation codons. ERBB2 CTFs resulting from either proteolytic shedding of the extracellular domain or alternative initiation of ERBB2 mRNA from methionine codon 611 contain the transmembrane domain and the intracellular domain (ICD) of the ERBB2 protein and maintain tyrosine kinase activity. Alternative initiation of ERBB2 mRNA from methionine codon 687 results in an ERBB2 CTF that only includes the ICD, which is soluble and localized to the cytoplasm and nucleus; this form does not appear to have tyrosine kinase activity." @default.
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• NCIT_C129898 normalizedInformationContent "100" @default.
• NCIT_C129898 referenceCount "1" @default.
• NCIT_C129898 hasExactSynonym "ERBB2 C-Terminal Fragment" @default.
• NCIT_C129898 hasExactSynonym "ERBB2 CTF" @default.
• NCIT_C129898 hasExactSynonym "ERBB2 Carboxyl Terminal Fragment" @default.
• NCIT_C129898 hasExactSynonym "ERBB2-p95" @default.
• NCIT_C129898 hasExactSynonym "HER2 C-Terminal Fragment" @default.
• NCIT_C129898 hasExactSynonym "HER2 CTF" @default.
• NCIT_C129898 hasExactSynonym "HER2-p95" @default.
• NCIT_C129898 hasExactSynonym "HER2/neu CTF" @default.
• NCIT_C129898 hasExactSynonym "HER2/neu-p95" @default.
• NCIT_C129898 hasExactSynonym "Receptor Tyrosine-Protein Kinase erbB-2 C-Terminal Fragment" @default.
• NCIT_C129898 hasExactSynonym "Receptor Tyrosine-Protein Kinase erbB-2 CTF" @default.
• NCIT_C129898 hasExactSynonym "Receptor Tyrosine-Protein Kinase erbB-2 Carboxyl Terminal Fragment" @default.
• NCIT_C129898 hasExactSynonym "p95 HER2" @default.
• NCIT_C129898 hasExactSynonym "p95HER2" @default.
• NCIT_C129898 inSubset NCIT_C116977 @default.
• NCIT_C129898 inSubset NCIT_C142799 @default.

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