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- NCIT_C1301 IAO_0000115 "An enediyne antineoplastic antibiotic hybrid containing an anthranilate moiety. Esperamicin A1 is isolated from the bacterium Actinomadura verrucosospora. The anthranilate component of esperamicin A1 intercalates DNA and the benzene diradical intermediate of the enediyne core binds to the minor groove of DNA, resulting in single- and double-stranded breaks in DNA and apoptosis. (NCI04)" @default.
- NCIT_C1301 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1301 NCIT_NHC0 "C1301" @default.
- NCIT_C1301 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1301 NCIT_P106 "Antibiotic" @default.
- NCIT_C1301 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1301 NCIT_P108 "Esperamicin A1" @default.
- NCIT_C1301 NCIT_P175 "372668" @default.
- NCIT_C1301 NCIT_P207 "C0082481" @default.
- NCIT_C1301 NCIT_P210 "99674-26-7" @default.
- NCIT_C1301 NCIT_P319 "PLX8T21X8G" @default.
- NCIT_C1301 NCIT_P322 "FDA" @default.
- NCIT_C1301 NCIT_P322 "GDC" @default.
- NCIT_C1301 NCIT_P366 "Esperamicin_A1" @default.
- NCIT_C1301 NCIT_P368 "CHEBI:53273" @default.
- NCIT_C1301 NCIT_P375 "Esperamicin A1" @default.
- NCIT_C1301 normalizedInformationContent "100" @default.
- NCIT_C1301 referenceCount "1" @default.
- NCIT_C1301 hasExactSynonym "ESPERAMICIN A1" @default.
- NCIT_C1301 hasExactSynonym "Esperamicin A1" @default.
- NCIT_C1301 inSubset NCIT_C128784 @default.
- NCIT_C1301 inSubset NCIT_C157711 @default.
- NCIT_C1301 inSubset NCIT_C157712 @default.
- NCIT_C1301 inSubset NCIT_C177537 @default.
- NCIT_C1301 inSubset NCIT_C63923 @default.
- NCIT_C1301 type Class @default.
- NCIT_C1301 isDefinedBy ncit.owl @default.
- NCIT_C1301 label "Esperamicin A1" @default.
- NCIT_C1301 subClassOf NCIT_C1301 @default.
- NCIT_C1301 subClassOf NCIT_C148123 @default.
- NCIT_C1301 subClassOf NCIT_C186664 @default.
- NCIT_C1301 subClassOf NCIT_C1908 @default.
- NCIT_C1301 subClassOf NCIT_C1909 @default.
- NCIT_C1301 subClassOf NCIT_C1927 @default.
- NCIT_C1301 subClassOf NCIT_C2163 @default.
- NCIT_C1301 subClassOf NCIT_C259 @default.
- NCIT_C1301 subClassOf NCIT_C274 @default.
- NCIT_C1301 subClassOf NCIT_C2842 @default.