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- NCIT_C1303 IAO_0000115 "A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin 11 (IL-11). Secreted by bone marrow stromal cells and a number of mesenchymal cells, IL-11 binds to and activates its cell-surface receptor, promoting primary and secondary immune responses, modulating antigen-specific antibody reactions, and preventing apoptotic cell death. This agent also stimulates the T-cell-dependent development of IgG-secreting B-cells in spleen cell cultures and may be an important regulator of megakaryocytopoiesis. (NCI04)" @default.
- NCIT_C1303 NCIT_NHC0 "C1303" @default.
- NCIT_C1303 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1303 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C1303 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1303 NCIT_P107 "Oprelvekin" @default.
- NCIT_C1303 NCIT_P108 "Oprelvekin" @default.
- NCIT_C1303 NCIT_P207 "C0537670" @default.
- NCIT_C1303 NCIT_P210 "145941-26-0" @default.
- NCIT_C1303 NCIT_P302 "Chemotherapy-related thrombocytopenia" @default.
- NCIT_C1303 NCIT_P319 "HM5641GA6F" @default.
- NCIT_C1303 NCIT_P322 "CTRP" @default.
- NCIT_C1303 NCIT_P322 "FDA" @default.
- NCIT_C1303 NCIT_P325 "A drug used to increase the number of blood cells, especially platelets, in some cancer patients receiving chemotherapy. Neumega is a form of interleukin-11 (a cytokine normally made by support cells in the bone marrow) that is made in the laboratory. It is a type of biological response modifier." @default.
- NCIT_C1303 NCIT_P329 "42365" @default.
- NCIT_C1303 NCIT_P330 "42365" @default.
- NCIT_C1303 NCIT_P366 "Therapeutic_Interleukin-11" @default.
- NCIT_C1303 NCIT_P399 "42365" @default.
- NCIT_C1303 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1303 NCIT_R125 NCIT_C18081 @default.
- NCIT_C1303 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1303 NCIT_R125 NCIT_C20751 @default.
- NCIT_C1303 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C1303 referenceCount "4" @default.
- NCIT_C1303 hasExactSynonym "Adipogenesis Inhibitory Factor" @default.
- NCIT_C1303 hasExactSynonym "IL-11" @default.
- NCIT_C1303 hasExactSynonym "Interleukin 11" @default.
- NCIT_C1303 hasExactSynonym "Interleukin-11" @default.
- NCIT_C1303 hasExactSynonym "Interleukin-11-Recombinant" @default.
- NCIT_C1303 hasExactSynonym "Neumega" @default.
- NCIT_C1303 hasExactSynonym "OPRELVEKIN" @default.
- NCIT_C1303 hasExactSynonym "Oprelvekin" @default.
- NCIT_C1303 hasExactSynonym "Recombinant Human Interleukin-11" @default.
- NCIT_C1303 hasExactSynonym "Recombinant Interleukin-11" @default.
- NCIT_C1303 hasExactSynonym "oprelvekin" @default.
- NCIT_C1303 hasExactSynonym "recombinant human interleukin-11" @default.
- NCIT_C1303 hasExactSynonym "rhIL-11" @default.
- NCIT_C1303 inSubset NCIT_C116977 @default.
- NCIT_C1303 inSubset NCIT_C116978 @default.
- NCIT_C1303 inSubset NCIT_C176424 @default.
- NCIT_C1303 inSubset NCIT_C63923 @default.
- NCIT_C1303 type Class @default.
- NCIT_C1303 isDefinedBy ncit.owl @default.
- NCIT_C1303 label "Oprelvekin" @default.
- NCIT_C1303 subClassOf NCIT_C1283 @default.
- NCIT_C1303 subClassOf NCIT_C1303 @default.
- NCIT_C1303 subClassOf NCIT_C1908 @default.
- NCIT_C1303 subClassOf NCIT_C1909 @default.
- NCIT_C1303 subClassOf NCIT_C307 @default.
- NCIT_C1303 subClassOf NCIT_C308 @default.
- NCIT_C1303 subClassOf NCIT_C593 @default.