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- NCIT_C1314 IAO_0000115 "A methotrexate derivative with potential antineoplastic activity. Trimetrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylate, with subsequent inhibition of DNA and RNA synthesis. Trimetrexate also exhibits antiviral activity. (NCI04)" @default.
- NCIT_C1314 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1314 NCIT_A5 NCIT_C1265 @default.
- NCIT_C1314 NCIT_NHC0 "C1314" @default.
- NCIT_C1314 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1314 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1314 NCIT_P108 "Trimetrexate" @default.
- NCIT_C1314 NCIT_P175 "249008" @default.
- NCIT_C1314 NCIT_P207 "C0085176" @default.
- NCIT_C1314 NCIT_P210 "52128-35-5" @default.
- NCIT_C1314 NCIT_P319 "UPN4ITI8T4" @default.
- NCIT_C1314 NCIT_P322 "FDA" @default.
- NCIT_C1314 NCIT_P322 "GDC" @default.
- NCIT_C1314 NCIT_P350 "C19H23N5O3" @default.
- NCIT_C1314 NCIT_P366 "Trimetrexate" @default.
- NCIT_C1314 NCIT_P375 "Trimetrexate" @default.
- NCIT_C1314 normalizedInformationContent "100" @default.
- NCIT_C1314 referenceCount "1" @default.
- NCIT_C1314 hasExactSynonym "2,4-Quinazolinediamine, 5-methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]-" @default.
- NCIT_C1314 hasExactSynonym "5-Methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]-2,4-quinazolinediamine" @default.
- NCIT_C1314 hasExactSynonym "CI-898" @default.
- NCIT_C1314 hasExactSynonym "TMQ" @default.
- NCIT_C1314 hasExactSynonym "TRIMETREXATE" @default.
- NCIT_C1314 hasExactSynonym "Trimetrexate" @default.
- NCIT_C1314 hasExactSynonym "Trimexate" @default.
- NCIT_C1314 inSubset NCIT_C128784 @default.
- NCIT_C1314 inSubset NCIT_C157711 @default.
- NCIT_C1314 inSubset NCIT_C157712 @default.
- NCIT_C1314 inSubset NCIT_C177537 @default.
- NCIT_C1314 inSubset NCIT_C63923 @default.
- NCIT_C1314 type Class @default.
- NCIT_C1314 isDefinedBy ncit.owl @default.
- NCIT_C1314 label "Trimetrexate" @default.
- NCIT_C1314 subClassOf NCIT_C1314 @default.
- NCIT_C1314 subClassOf NCIT_C186664 @default.
- NCIT_C1314 subClassOf NCIT_C1908 @default.
- NCIT_C1314 subClassOf NCIT_C1909 @default.
- NCIT_C1314 subClassOf NCIT_C2153 @default.
- NCIT_C1314 subClassOf NCIT_C272 @default.
- NCIT_C1314 subClassOf NCIT_C274 @default.
- NCIT_C1314 subClassOf NCIT_C471 @default.
- NCIT_C1314 subClassOf NCIT_C511 @default.