Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C131493> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- NCIT_C131493 IAO_0000115 "A preparation of autologous, engineered T-lymphocytes that express both a second-generation chimeric antigen receptor (CAR) specific for the human gastric carcinoma-associated antigen MG7, and the co-stimulatory molecule 4-1BB (CD137), with potential antineoplastic activity. Upon intratumoral injection, the autologous anti-MG7-CAR T-lymphocytes target and attach to cancer cells expressing MG7. This induces selective toxicity in and causes lysis of MG7-expressing tumor cells. MG7, a glycosylated protein sequence from the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), plays a key role in the development of certain tumor cell types. 4-1BB enhances T-cell activation and signaling after recognition of MG7." @default.
- NCIT_C131493 NCIT_A7 NCIT_C178660 @default.
- NCIT_C131493 NCIT_NHC0 "C131493" @default.
- NCIT_C131493 NCIT_P106 "Cell" @default.
- NCIT_C131493 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C131493 NCIT_P108 "Autologous Anti-MG7-CAR T-Lymphocytes" @default.
- NCIT_C131493 NCIT_P208 "CL514248" @default.
- NCIT_C131493 NCIT_P329 "785816" @default.
- NCIT_C131493 NCIT_P330 "785816" @default.
- NCIT_C131493 NCIT_P399 "785816" @default.
- NCIT_C131493 NCIT_R124 NCIT_C17828 @default.
- NCIT_C131493 NCIT_R124 NCIT_C17930 @default.
- NCIT_C131493 NCIT_R124 NCIT_C17937 @default.
- NCIT_C131493 NCIT_R124 NCIT_C18839 @default.
- NCIT_C131493 NCIT_R124 NCIT_C21124 @default.
- NCIT_C131493 NCIT_R124 NCIT_C45548 @default.
- NCIT_C131493 NCIT_R125 NCIT_C17828 @default.
- NCIT_C131493 NCIT_R125 NCIT_C17937 @default.
- NCIT_C131493 NCIT_R125 NCIT_C18095 @default.
- NCIT_C131493 NCIT_R125 NCIT_C18839 @default.
- NCIT_C131493 NCIT_R125 NCIT_C19053 @default.
- NCIT_C131493 NCIT_R125 NCIT_C21124 @default.
- NCIT_C131493 NCIT_R125 NCIT_C26280 @default.
- NCIT_C131493 NCIT_R125 NCIT_C40833 @default.
- NCIT_C131493 NCIT_R125 NCIT_C40912 @default.
- NCIT_C131493 NCIT_R72 NCIT_C104083 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12219 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12476 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12508 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12535 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12542 @default.
- NCIT_C131493 NCIT_R72 NCIT_C12543 @default.
- NCIT_C131493 NCIT_R72 NCIT_C21599 @default.
- NCIT_C131493 NCIT_R72 NCIT_C32725 @default.
- NCIT_C131493 NCIT_R72 NCIT_C33061 @default.
- NCIT_C131493 NCIT_R72 NCIT_C38434 @default.
- NCIT_C131493 NCIT_R72 NCIT_C38439 @default.
- NCIT_C131493 NCIT_R72 NCIT_C39567 @default.
- NCIT_C131493 NCIT_R72 NCIT_C39568 @default.
- NCIT_C131493 normalizedInformationContent "100" @default.
- NCIT_C131493 referenceCount "1" @default.
- NCIT_C131493 hasExactSynonym "Autologous Anti-MG7 CAR-T Cells" @default.
- NCIT_C131493 hasExactSynonym "Autologous Anti-MG7-CAR T Lymphocytes" @default.
- NCIT_C131493 hasExactSynonym "Autologous Anti-MG7-CAR T-Lymphocytes" @default.
- NCIT_C131493 hasExactSynonym "Autologous MG7-CART Cells" @default.
- NCIT_C131493 hasExactSynonym "Autologous MG7-CART" @default.
- NCIT_C131493 hasExactSynonym "MG7-targeted Chimeric Antigen Receptor T Cells" @default.
- NCIT_C131493 inSubset NCIT_C128784 @default.
- NCIT_C131493 inSubset NCIT_C176424 @default.
- NCIT_C131493 type Class @default.
- NCIT_C131493 isDefinedBy ncit.owl @default.
- NCIT_C131493 label "Autologous Anti-MG7-CAR T-Lymphocytes" @default.
- NCIT_C131493 subClassOf NCIT_C129820 @default.
- NCIT_C131493 subClassOf NCIT_C129821 @default.
- NCIT_C131493 subClassOf NCIT_C129826 @default.
- NCIT_C131493 subClassOf NCIT_C131493 @default.
- NCIT_C131493 subClassOf NCIT_C137999 @default.
- NCIT_C131493 subClassOf NCIT_C142078 @default.
- NCIT_C131493 subClassOf NCIT_C154231 @default.
- NCIT_C131493 subClassOf NCIT_C1908 @default.
- NCIT_C131493 subClassOf NCIT_C1909 @default.
- NCIT_C131493 subClassOf NCIT_C1962 @default.
- NCIT_C131493 subClassOf NCIT_C200766 @default.
- NCIT_C131493 subClassOf NCIT_C274 @default.
- NCIT_C131493 subClassOf NCIT_C28681 @default.
- NCIT_C131493 subClassOf NCIT_C307 @default.
- NCIT_C131493 subClassOf NCIT_C308 @default.