Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C131537> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- NCIT_C131537 IAO_0000115 "A monoclonal antibody directed against programmed cell death-1 ligand 1 (PD-L1), with immune checkpoint inhibitory and potential antineoplastic activities. Upon administration, anti-PD-L1 monoclonal antibody FAZ053 binds to PD-L1, blocking its binding to and activation of its receptor programmed death 1 (PD-1), which may enhance the T-cell-mediated anti-tumor immune response and reverse T-cell inactivation. PD-L1 is overexpressed by many human cancer cell types. PD-L1 binding to PD-1 on T-cells suppresses the immune system and results in immune evasion. PD-1, a transmembrane protein expressed on activated T-cells, is a negative regulator of the immune system that limits the expansion and survival of CD8+ T-cells." @default.
- NCIT_C131537 NCIT_A32 NCIT_C1909 @default.
- NCIT_C131537 NCIT_A7 NCIT_C96024 @default.
- NCIT_C131537 NCIT_NHC0 "C131537" @default.
- NCIT_C131537 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C131537 NCIT_P107 "Anti-PD-L1 Monoclonal Antibody FAZ053" @default.
- NCIT_C131537 NCIT_P108 "Anti-PD-L1 Monoclonal Antibody FAZ053" @default.
- NCIT_C131537 NCIT_P208 "CL514246" @default.
- NCIT_C131537 NCIT_P319 "V6W1OW12H2" @default.
- NCIT_C131537 NCIT_P322 "CTRP" @default.
- NCIT_C131537 NCIT_P322 "FDA" @default.
- NCIT_C131537 NCIT_P322 "GDC" @default.
- NCIT_C131537 NCIT_P329 "786263" @default.
- NCIT_C131537 NCIT_P330 "786263" @default.
- NCIT_C131537 NCIT_P375 "Anti-PD-L1 Monoclonal Antibody FAZ053" @default.
- NCIT_C131537 NCIT_P399 "786263" @default.
- NCIT_C131537 NCIT_R124 NCIT_C17710 @default.
- NCIT_C131537 NCIT_R124 NCIT_C17828 @default.
- NCIT_C131537 NCIT_R124 NCIT_C18219 @default.
- NCIT_C131537 NCIT_R124 NCIT_C19986 @default.
- NCIT_C131537 NCIT_R124 NCIT_C40474 @default.
- NCIT_C131537 normalizedInformationContent "100" @default.
- NCIT_C131537 referenceCount "1" @default.
- NCIT_C131537 hasExactSynonym "Anti-PD-L1 Monoclonal Antibody FAZ053" @default.
- NCIT_C131537 hasExactSynonym "FAZ 053" @default.
- NCIT_C131537 hasExactSynonym "FAZ-053" @default.
- NCIT_C131537 hasExactSynonym "FAZ053" @default.
- NCIT_C131537 inSubset NCIT_C116977 @default.
- NCIT_C131537 inSubset NCIT_C116978 @default.
- NCIT_C131537 inSubset NCIT_C128784 @default.
- NCIT_C131537 inSubset NCIT_C157711 @default.
- NCIT_C131537 inSubset NCIT_C157712 @default.
- NCIT_C131537 inSubset NCIT_C176424 @default.
- NCIT_C131537 inSubset NCIT_C177537 @default.
- NCIT_C131537 inSubset NCIT_C63923 @default.
- NCIT_C131537 type Class @default.
- NCIT_C131537 isDefinedBy ncit.owl @default.
- NCIT_C131537 label "Anti-PD-L1 Monoclonal Antibody FAZ053" @default.
- NCIT_C131537 subClassOf NCIT_C128057 @default.
- NCIT_C131537 subClassOf NCIT_C129821 @default.
- NCIT_C131537 subClassOf NCIT_C129822 @default.
- NCIT_C131537 subClassOf NCIT_C131537 @default.
- NCIT_C131537 subClassOf NCIT_C141144 @default.
- NCIT_C131537 subClassOf NCIT_C143250 @default.
- NCIT_C131537 subClassOf NCIT_C156893 @default.
- NCIT_C131537 subClassOf NCIT_C163758 @default.
- NCIT_C131537 subClassOf NCIT_C1908 @default.
- NCIT_C131537 subClassOf NCIT_C1909 @default.
- NCIT_C131537 subClassOf NCIT_C191689 @default.
- NCIT_C131537 subClassOf NCIT_C20401 @default.
- NCIT_C131537 subClassOf NCIT_C274 @default.
- NCIT_C131537 subClassOf NCIT_C307 @default.
- NCIT_C131537 subClassOf NCIT_C308 @default.