Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C132252> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- NCIT_C132252 IAO_0000115 "A monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed cell death protein 1 (PD-1; PDCD1), with immune checkpoint inhibitory and antineoplastic activities. Upon administration, ezabenlimab selectively binds to and blocks the activation of PD-1, an immunoglobulin (Ig) superfamily transmembrane protein, by its ligands programmed cell death ligand 1 (PD-L1), which is overexpressed on certain cancer cells, and programmed cell death ligand 2 (PD-L2), which is primarily expressed on antigen-presenting cells (APCs). This results in the activation of T-cells and T-cell-mediated immune responses against tumor cells. Activated PD-1 negatively regulates T-cell activation and plays a key role in in tumor evasion from host immunity." @default.
- NCIT_C132252 NCIT_A32 NCIT_C1909 @default.
- NCIT_C132252 NCIT_A7 NCIT_C94697 @default.
- NCIT_C132252 NCIT_NHC0 "C132252" @default.
- NCIT_C132252 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C132252 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C132252 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C132252 NCIT_P107 "Ezabenlimab" @default.
- NCIT_C132252 NCIT_P108 "Ezabenlimab" @default.
- NCIT_C132252 NCIT_P208 "CL520361" @default.
- NCIT_C132252 NCIT_P210 "2249882-54-8" @default.
- NCIT_C132252 NCIT_P319 "5V1UI86573" @default.
- NCIT_C132252 NCIT_P322 "CTRP" @default.
- NCIT_C132252 NCIT_P322 "FDA" @default.
- NCIT_C132252 NCIT_P322 "GDC" @default.
- NCIT_C132252 NCIT_P329 "787036" @default.
- NCIT_C132252 NCIT_P330 "787036" @default.
- NCIT_C132252 NCIT_P375 "Anti-PD-1 Monoclonal Antibody BI 754091" @default.
- NCIT_C132252 NCIT_P375 "Ezabenlimab" @default.
- NCIT_C132252 NCIT_P399 "787036" @default.
- NCIT_C132252 NCIT_R124 NCIT_C17710 @default.
- NCIT_C132252 NCIT_R124 NCIT_C17828 @default.
- NCIT_C132252 NCIT_R124 NCIT_C18219 @default.
- NCIT_C132252 NCIT_R124 NCIT_C19986 @default.
- NCIT_C132252 NCIT_R124 NCIT_C40474 @default.
- NCIT_C132252 normalizedInformationContent "100" @default.
- NCIT_C132252 referenceCount "1" @default.
- NCIT_C132252 hasExactSynonym "Anti-PD-1 Monoclonal Antibody BI 754091" @default.
- NCIT_C132252 hasExactSynonym "BI 754091" @default.
- NCIT_C132252 hasExactSynonym "EZABENLIMAB" @default.
- NCIT_C132252 hasExactSynonym "Ezabenlimab" @default.
- NCIT_C132252 inSubset NCIT_C116977 @default.
- NCIT_C132252 inSubset NCIT_C116978 @default.
- NCIT_C132252 inSubset NCIT_C128784 @default.
- NCIT_C132252 inSubset NCIT_C157711 @default.
- NCIT_C132252 inSubset NCIT_C157712 @default.
- NCIT_C132252 inSubset NCIT_C176424 @default.
- NCIT_C132252 inSubset NCIT_C177537 @default.
- NCIT_C132252 inSubset NCIT_C63923 @default.
- NCIT_C132252 type Class @default.
- NCIT_C132252 isDefinedBy ncit.owl @default.
- NCIT_C132252 label "Ezabenlimab" @default.
- NCIT_C132252 subClassOf NCIT_C124946 @default.
- NCIT_C132252 subClassOf NCIT_C128037 @default.
- NCIT_C132252 subClassOf NCIT_C129821 @default.
- NCIT_C132252 subClassOf NCIT_C129822 @default.
- NCIT_C132252 subClassOf NCIT_C132252 @default.
- NCIT_C132252 subClassOf NCIT_C141144 @default.
- NCIT_C132252 subClassOf NCIT_C143250 @default.
- NCIT_C132252 subClassOf NCIT_C163758 @default.
- NCIT_C132252 subClassOf NCIT_C1908 @default.
- NCIT_C132252 subClassOf NCIT_C1909 @default.
- NCIT_C132252 subClassOf NCIT_C20401 @default.
- NCIT_C132252 subClassOf NCIT_C274 @default.
- NCIT_C132252 subClassOf NCIT_C307 @default.
- NCIT_C132252 subClassOf NCIT_C308 @default.