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- NCIT_C133174 IAO_0000115 "An inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential pro-apoptotic and antineoplastic activities. Upon administration, MIK665 binds to and inhibits the activity of Mcl-1, which promotes apoptosis of cells overexpressing Mcl-1. Mcl-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival." @default.
- NCIT_C133174 NCIT_A32 NCIT_C1909 @default.
- NCIT_C133174 NCIT_A7 NCIT_C17688 @default.
- NCIT_C133174 NCIT_NHC0 "C133174" @default.
- NCIT_C133174 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C133174 NCIT_P107 "Mcl-1 Inhibitor MIK665" @default.
- NCIT_C133174 NCIT_P108 "Mcl-1 Inhibitor MIK665" @default.
- NCIT_C133174 NCIT_P208 "CL520448" @default.
- NCIT_C133174 NCIT_P210 "1799638-19-9" @default.
- NCIT_C133174 NCIT_P319 "801XYWHNOS" @default.
- NCIT_C133174 NCIT_P322 "CTRP" @default.
- NCIT_C133174 NCIT_P322 "FDA" @default.
- NCIT_C133174 NCIT_P322 "GDC" @default.
- NCIT_C133174 NCIT_P329 "788002" @default.
- NCIT_C133174 NCIT_P330 "788002" @default.
- NCIT_C133174 NCIT_P375 "Mcl-1 Inhibitor MIK665" @default.
- NCIT_C133174 NCIT_P399 "788002" @default.
- NCIT_C133174 normalizedInformationContent "100" @default.
- NCIT_C133174 referenceCount "1" @default.
- NCIT_C133174 hasExactSynonym "MIK 665" @default.
- NCIT_C133174 hasExactSynonym "MIK-665" @default.
- NCIT_C133174 hasExactSynonym "MIK665" @default.
- NCIT_C133174 hasExactSynonym "Mcl-1 Inhibitor MIK665" @default.
- NCIT_C133174 hasExactSynonym "S 64315" @default.
- NCIT_C133174 hasExactSynonym "S-64315" @default.
- NCIT_C133174 hasExactSynonym "S64315" @default.
- NCIT_C133174 inSubset NCIT_C116977 @default.
- NCIT_C133174 inSubset NCIT_C116978 @default.
- NCIT_C133174 inSubset NCIT_C128784 @default.
- NCIT_C133174 inSubset NCIT_C157711 @default.
- NCIT_C133174 inSubset NCIT_C157712 @default.
- NCIT_C133174 inSubset NCIT_C176424 @default.
- NCIT_C133174 inSubset NCIT_C177537 @default.
- NCIT_C133174 inSubset NCIT_C63923 @default.
- NCIT_C133174 type Class @default.
- NCIT_C133174 isDefinedBy ncit.owl @default.
- NCIT_C133174 label "Mcl-1 Inhibitor MIK665" @default.
- NCIT_C133174 subClassOf NCIT_C129839 @default.
- NCIT_C133174 subClassOf NCIT_C133174 @default.
- NCIT_C133174 subClassOf NCIT_C137990 @default.
- NCIT_C133174 subClassOf NCIT_C1908 @default.
- NCIT_C133174 subClassOf NCIT_C1909 @default.
- NCIT_C133174 subClassOf NCIT_C192025 @default.
- NCIT_C133174 subClassOf NCIT_C274 @default.