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- NCIT_C133818 IAO_0000115 "An antibody drug conjugate (ADC) composed of a monoclonal antibody that targets the tumor-associated antigen (TAA) AG7 and is linked, through a hydrophilic, self-immolative linker, to a proprietary cytotoxic payload, with potential antineoplastic activity. Upon administration of AbGn-107 the antibody moiety targets and binds to the AG7 antigen expressed on a variety of cancer cells. Upon binding and internalization, the linker is cleaved and the payload is released, binds to tubulin, inhibits tubulin polymerization and kills the AG7-expressing tumor cells." @default.
- NCIT_C133818 NCIT_A32 NCIT_C1909 @default.
- NCIT_C133818 NCIT_NHC0 "C133818" @default.
- NCIT_C133818 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C133818 NCIT_P107 "Anti-AG7 Antibody Drug Conjugate AbGn-107" @default.
- NCIT_C133818 NCIT_P108 "Anti-AG7 Antibody Drug Conjugate AbGn-107" @default.
- NCIT_C133818 NCIT_P208 "CL521740" @default.
- NCIT_C133818 NCIT_P322 "CTRP" @default.
- NCIT_C133818 NCIT_P322 "GDC" @default.
- NCIT_C133818 NCIT_P329 "789018" @default.
- NCIT_C133818 NCIT_P330 "789018" @default.
- NCIT_C133818 NCIT_P375 "Anti-AG7 Antibody Drug Conjugate AbGn-107" @default.
- NCIT_C133818 NCIT_P399 "789018" @default.
- NCIT_C133818 normalizedInformationContent "100" @default.
- NCIT_C133818 referenceCount "1" @default.
- NCIT_C133818 hasExactSynonym "ADC AbGn-107" @default.
- NCIT_C133818 hasExactSynonym "Ab1-18Hr1" @default.
- NCIT_C133818 hasExactSynonym "AbGn-107" @default.
- NCIT_C133818 hasExactSynonym "AbGn107" @default.
- NCIT_C133818 hasExactSynonym "Anti-AG7 ADC AbGn-107" @default.
- NCIT_C133818 hasExactSynonym "Anti-AG7 Antibody Drug Conjugate AbGn-107" @default.
- NCIT_C133818 inSubset NCIT_C116977 @default.
- NCIT_C133818 inSubset NCIT_C116978 @default.
- NCIT_C133818 inSubset NCIT_C128784 @default.
- NCIT_C133818 inSubset NCIT_C157711 @default.
- NCIT_C133818 inSubset NCIT_C157712 @default.
- NCIT_C133818 inSubset NCIT_C176424 @default.
- NCIT_C133818 inSubset NCIT_C177537 @default.
- NCIT_C133818 type Class @default.
- NCIT_C133818 isDefinedBy ncit.owl @default.
- NCIT_C133818 label "Anti-AG7 Antibody Drug Conjugate AbGn-107" @default.
- NCIT_C133818 subClassOf NCIT_C133818 @default.
- NCIT_C133818 subClassOf NCIT_C1512 @default.
- NCIT_C133818 subClassOf NCIT_C1908 @default.
- NCIT_C133818 subClassOf NCIT_C1909 @default.
- NCIT_C133818 subClassOf NCIT_C307 @default.
- NCIT_C133818 subClassOf NCIT_C308 @default.