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- NCIT_C134829 IAO_0000115 "A long-acting form and covalent conjugate of recombinant human granulocyte colony-stimulating factor (G-CSF) filgrastim with 30 kDa polyethylene glycol (PEG), with potential hematopoietic activity. Upon administration, empegfilgrastim acts similarly to endogenous G-CSF and binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Therefore, this agent may prevent the incidence and shorten the duration of chemotherapy-induced neutropenia. Conjugation of the cytokine with a PEG molecule significantly increases this agent's therapeutic half-life compared to filgrastim." @default.
- NCIT_C134829 NCIT_NHC0 "C134829" @default.
- NCIT_C134829 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C134829 NCIT_P108 "Empegfilgrastim" @default.
- NCIT_C134829 NCIT_P208 "CL522347" @default.
- NCIT_C134829 NCIT_P210 "1192706-53-8" @default.
- NCIT_C134829 NCIT_P319 "F0B69ZZ07A" @default.
- NCIT_C134829 NCIT_P322 "FDA" @default.
- NCIT_C134829 NCIT_P399 "805140" @default.
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- NCIT_C134829 NCIT_R72 NCIT_C12219 @default.
- NCIT_C134829 NCIT_R72 NCIT_C12508 @default.
- NCIT_C134829 NCIT_R72 NCIT_C12551 @default.
- NCIT_C134829 NCIT_R72 NCIT_C12662 @default.
- NCIT_C134829 NCIT_R72 NCIT_C21599 @default.
- NCIT_C134829 NCIT_R72 NCIT_C32725 @default.
- NCIT_C134829 normalizedInformationContent "100" @default.
- NCIT_C134829 referenceCount "1" @default.
- NCIT_C134829 hasExactSynonym "1-(N-(4-(omega-Methoxypoly(oxyethylene))butyl)-L-methionine))human granulocyte colony-stimulating factor (pluripoietin)" @default.
- NCIT_C134829 hasExactSynonym "BCD 017" @default.
- NCIT_C134829 hasExactSynonym "BCD-017" @default.
- NCIT_C134829 hasExactSynonym "BCD017" @default.
- NCIT_C134829 hasExactSynonym "EMPEGFILGRASTIM" @default.
- NCIT_C134829 hasExactSynonym "Empegfilgrastim" @default.
- NCIT_C134829 inSubset NCIT_C176424 @default.
- NCIT_C134829 inSubset NCIT_C63923 @default.
- NCIT_C134829 type Class @default.
- NCIT_C134829 isDefinedBy ncit.owl @default.
- NCIT_C134829 label "Empegfilgrastim" @default.
- NCIT_C134829 subClassOf NCIT_C1283 @default.
- NCIT_C134829 subClassOf NCIT_C1287 @default.
- NCIT_C134829 subClassOf NCIT_C134829 @default.
- NCIT_C134829 subClassOf NCIT_C1908 @default.
- NCIT_C134829 subClassOf NCIT_C1909 @default.
- NCIT_C134829 subClassOf NCIT_C2395 @default.
- NCIT_C134829 subClassOf NCIT_C307 @default.
- NCIT_C134829 subClassOf NCIT_C308 @default.
- NCIT_C134829 subClassOf NCIT_C387 @default.
- NCIT_C134829 subClassOf NCIT_C530 @default.