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- NCIT_C135189 IAO_0000115 "A formulation containing the hydrochloride salt form of diphenoxylate, a synthetic opioid of the phenylpiperidine class, and the sulfate salt form of the anticholinergic agent atropine, with antidiarrheal activity. Upon oral administration, diphenoxylate acts on opioid receptors in the gastrointestinal (GI) tract, thereby decreasing GI motility, prolonging transit time, and preventing diarrhea. Through its anticholinergic effects, atropine prevents deliberate over-usage of diphenoxylate by triggering very unpleasant side effects (SEs), such as severe weakness and nausea." @default.
- NCIT_C135189 NCIT_NHC0 "C135189" @default.
- NCIT_C135189 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C135189 NCIT_P107 "Diphenoxylate Hydrochloride/Atropine Sulfate" @default.
- NCIT_C135189 NCIT_P108 "Diphenoxylate Hydrochloride/Atropine Sulfate" @default.
- NCIT_C135189 NCIT_P207 "C0065164" @default.
- NCIT_C135189 NCIT_P322 "CTRP" @default.
- NCIT_C135189 normalizedInformationContent "100" @default.
- NCIT_C135189 referenceCount "1" @default.
- NCIT_C135189 hasExactSynonym "Diphenoxylate Hydrochloride and Atropine Sulfate" @default.
- NCIT_C135189 hasExactSynonym "Diphenoxylate Hydrochloride/Atropine Sulfate" @default.
- NCIT_C135189 hasExactSynonym "Lomotil" @default.
- NCIT_C135189 inSubset NCIT_C116977 @default.
- NCIT_C135189 inSubset NCIT_C116978 @default.
- NCIT_C135189 inSubset NCIT_C176424 @default.
- NCIT_C135189 type Class @default.
- NCIT_C135189 isDefinedBy ncit.owl @default.
- NCIT_C135189 label "Diphenoxylate Hydrochloride/Atropine Sulfate" @default.
- NCIT_C135189 subClassOf NCIT_C135189 @default.
- NCIT_C135189 subClassOf NCIT_C1908 @default.
- NCIT_C135189 subClassOf NCIT_C1909 @default.
- NCIT_C135189 subClassOf NCIT_C266 @default.
- NCIT_C135189 subClassOf NCIT_C29629 @default.
- NCIT_C135189 subClassOf NCIT_C78276 @default.