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- NCIT_C135613 IAO_0000115 "A solution for inhalation containing the aminoglycoside antibiotic amikacin, with anti-bacterial activity. Upon aerosolized administration using the Pulmonary Drug Delivery System (PDDS), amikacin irreversibly binds to the 30S ribosomal subunit of susceptible organisms, thereby interfering with the activity of the translation initiation complex, which leads to both the misreading of mRNA and the production of non-functional or toxic peptides, and prevents normal protein synthesis. This kills susceptible bacteria." @default.
- NCIT_C135613 NCIT_NHC0 "C135613" @default.
- NCIT_C135613 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C135613 NCIT_P107 "Amikacin Inhalation Solution" @default.
- NCIT_C135613 NCIT_P108 "Amikacin Inhalation Solution" @default.
- NCIT_C135613 NCIT_P208 "CL522969" @default.
- NCIT_C135613 NCIT_P322 "CTRP" @default.
- NCIT_C135613 NCIT_P329 "789495" @default.
- NCIT_C135613 NCIT_P330 "789495" @default.
- NCIT_C135613 NCIT_P399 "789495" @default.
- NCIT_C135613 normalizedInformationContent "100" @default.
- NCIT_C135613 referenceCount "1" @default.
- NCIT_C135613 hasExactSynonym "Amikacin Inhalation Solution" @default.
- NCIT_C135613 hasExactSynonym "BAY41 6551" @default.
- NCIT_C135613 hasExactSynonym "BAY41-6551" @default.
- NCIT_C135613 inSubset NCIT_C116977 @default.
- NCIT_C135613 inSubset NCIT_C116978 @default.
- NCIT_C135613 inSubset NCIT_C176424 @default.
- NCIT_C135613 type Class @default.
- NCIT_C135613 isDefinedBy ncit.owl @default.
- NCIT_C135613 label "Amikacin Inhalation Solution" @default.
- NCIT_C135613 subClassOf NCIT_C135613 @default.
- NCIT_C135613 subClassOf NCIT_C1908 @default.
- NCIT_C135613 subClassOf NCIT_C1909 @default.
- NCIT_C135613 subClassOf NCIT_C2363 @default.
- NCIT_C135613 subClassOf NCIT_C254 @default.
- NCIT_C135613 subClassOf NCIT_C258 @default.
- NCIT_C135613 subClassOf NCIT_C784 @default.