Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C135619> ?p ?o ?g. }
Showing items 1 to 39 of
39
with 100 items per page.
- NCIT_C135619 IAO_0000115 "A formulation of the tartrate salt form of vinorelbine, a semisynthetic vinca alkaloid, encapsulated within liposomes, with potential antineoplastic activity. Upon intravenous administration, vinorelbine binds to tubulin within tumor cells and prevents the formation of the mitotic spindle, resulting in cell cycle arrest, induction of apoptosis and an inhibition of tumor cell growth. Compared to the administration of vinorelbine alone, the liposomal formulation improves drug penetration into tumors and decreases drug clearance, thereby increasing vinorelbine's efficacy while lowering the toxicity profile." @default.
- NCIT_C135619 NCIT_A32 NCIT_C1909 @default.
- NCIT_C135619 NCIT_A7 NCIT_C129655 @default.
- NCIT_C135619 NCIT_NHC0 "C135619" @default.
- NCIT_C135619 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C135619 NCIT_P107 "Liposomal Vinorelbine Tartrate" @default.
- NCIT_C135619 NCIT_P108 "Liposomal Vinorelbine Tartrate" @default.
- NCIT_C135619 NCIT_P208 "CL522975" @default.
- NCIT_C135619 NCIT_P322 "CTRP" @default.
- NCIT_C135619 NCIT_P322 "GDC" @default.
- NCIT_C135619 NCIT_P329 "789502" @default.
- NCIT_C135619 NCIT_P330 "789502" @default.
- NCIT_C135619 NCIT_P375 "Liposomal Vinorelbine Tartrate" @default.
- NCIT_C135619 NCIT_P399 "789502" @default.
- NCIT_C135619 normalizedInformationContent "100" @default.
- NCIT_C135619 referenceCount "1" @default.
- NCIT_C135619 hasExactSynonym "Liposomal Vinorelbine Tartrate" @default.
- NCIT_C135619 hasExactSynonym "TLC-178" @default.
- NCIT_C135619 hasExactSynonym "TLC178" @default.
- NCIT_C135619 inSubset NCIT_C116977 @default.
- NCIT_C135619 inSubset NCIT_C116978 @default.
- NCIT_C135619 inSubset NCIT_C157711 @default.
- NCIT_C135619 inSubset NCIT_C157712 @default.
- NCIT_C135619 inSubset NCIT_C176424 @default.
- NCIT_C135619 inSubset NCIT_C177537 @default.
- NCIT_C135619 type Class @default.
- NCIT_C135619 isDefinedBy ncit.owl @default.
- NCIT_C135619 label "Liposomal Vinorelbine Tartrate" @default.
- NCIT_C135619 subClassOf NCIT_C135619 @default.
- NCIT_C135619 subClassOf NCIT_C1907 @default.
- NCIT_C135619 subClassOf NCIT_C1908 @default.
- NCIT_C135619 subClassOf NCIT_C1909 @default.
- NCIT_C135619 subClassOf NCIT_C1913 @default.
- NCIT_C135619 subClassOf NCIT_C1916 @default.
- NCIT_C135619 subClassOf NCIT_C1931 @default.
- NCIT_C135619 subClassOf NCIT_C221 @default.
- NCIT_C135619 subClassOf NCIT_C274 @default.
- NCIT_C135619 subClassOf NCIT_C718 @default.
- NCIT_C135619 subClassOf NCIT_C932 @default.