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- NCIT_C135631 IAO_0000115 "An orally bioavailable dietary supplement composed of an extract from grape seeds containing high amounts of polyphenols, particularly lower proanthocyanidin oligomers (OPCs) and catechins, with antioxidant and chemopreventive activities. Upon administration, the active components in the grape seed extract (GSE) scavenge free radicals, protect against oxidation of low-density lipoprotein (LDL), and inhibit cell damage due to reactive oxygen species (ROS). This inhibits oxidative stress and protects against DNA damage. GSE also inhibits enzymes involved in inflammation, cell replication and DNA synthesis, and induces the expression of anti-oxidant enzymes. This may inhibit growth and induce apoptosis of cancer cells." @default.
- NCIT_C135631 NCIT_NHC0 "C135631" @default.
- NCIT_C135631 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C135631 NCIT_P107 "Grape Seed Extract Supplement" @default.
- NCIT_C135631 NCIT_P108 "Grape Seed Extract Supplement" @default.
- NCIT_C135631 NCIT_P208 "CL522986" @default.
- NCIT_C135631 NCIT_P322 "CTRP" @default.
- NCIT_C135631 NCIT_P329 "789016" @default.
- NCIT_C135631 NCIT_P330 "789016" @default.
- NCIT_C135631 NCIT_P399 "789016" @default.
- NCIT_C135631 normalizedInformationContent "100" @default.
- NCIT_C135631 referenceCount "1" @default.
- NCIT_C135631 hasExactSynonym "GSE Supplement" @default.
- NCIT_C135631 hasExactSynonym "GSE" @default.
- NCIT_C135631 hasExactSynonym "Grape Seed Extract Supplement" @default.
- NCIT_C135631 inSubset NCIT_C116977 @default.
- NCIT_C135631 inSubset NCIT_C116978 @default.
- NCIT_C135631 inSubset NCIT_C176424 @default.
- NCIT_C135631 type Class @default.
- NCIT_C135631 isDefinedBy ncit.owl @default.
- NCIT_C135631 label "Grape Seed Extract Supplement" @default.
- NCIT_C135631 subClassOf NCIT_C135631 @default.
- NCIT_C135631 subClassOf NCIT_C1505 @default.
- NCIT_C135631 subClassOf NCIT_C1908 @default.
- NCIT_C135631 subClassOf NCIT_C1909 @default.
- NCIT_C135631 subClassOf NCIT_C26170 @default.