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- NCIT_C1359 IAO_0000115 "A pro-drug carbocyclic analogue of cytidine with antineoplastic and antiviral activities. Cyclopentenyl cytosine (CPEC) is converted to the active metabolite cyclopentenyl cytosine 5'-triphosphate (CPEC-TP); CPEC-TP competitively inhibits cytidine triphosphate (CTP) synthase, thereby depleting intracellular cytidine pools and inhibiting DNA and RNA synthesis. This agent may also induce differentiation of some tumor cell types. The antiviral activity of this agent is broad-spectrum." @default.
- NCIT_C1359 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1359 NCIT_NHC0 "C1359" @default.
- NCIT_C1359 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C1359 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1359 NCIT_P108 "Cyclopentenyl Cytosine" @default.
- NCIT_C1359 NCIT_P175 "375575" @default.
- NCIT_C1359 NCIT_P207 "C0111606" @default.
- NCIT_C1359 NCIT_P210 "90597-22-1" @default.
- NCIT_C1359 NCIT_P319 "69MO0NDN8K" @default.
- NCIT_C1359 NCIT_P322 "FDA" @default.
- NCIT_C1359 NCIT_P322 "GDC" @default.
- NCIT_C1359 NCIT_P329 "41433" @default.
- NCIT_C1359 NCIT_P330 "41433" @default.
- NCIT_C1359 NCIT_P366 "Cyclopentenyl_Cytosine" @default.
- NCIT_C1359 NCIT_P375 "Cyclopentenyl Cytosine" @default.
- NCIT_C1359 NCIT_P399 "41433" @default.
- NCIT_C1359 normalizedInformationContent "100" @default.
- NCIT_C1359 referenceCount "1" @default.
- NCIT_C1359 hasExactSynonym "2(1H)-Pyrimidinone, 4-amino-1-[4, 5-dihydroxy- 3-(hydroxymethyl)-2-cyclopenten-1-yl]-" @default.
- NCIT_C1359 hasExactSynonym "CPE-C" @default.
- NCIT_C1359 hasExactSynonym "CYCLOPENTENYL CYTOSINE" @default.
- NCIT_C1359 hasExactSynonym "Cyclopentenyl Cytosine" @default.
- NCIT_C1359 hasExactSynonym "Cyclopentenylcytosine Triphosphate" @default.
- NCIT_C1359 hasExactSynonym "Cyclopentenylcytosine" @default.
- NCIT_C1359 inSubset NCIT_C128784 @default.
- NCIT_C1359 inSubset NCIT_C157711 @default.
- NCIT_C1359 inSubset NCIT_C157712 @default.
- NCIT_C1359 inSubset NCIT_C176424 @default.
- NCIT_C1359 inSubset NCIT_C177537 @default.
- NCIT_C1359 inSubset NCIT_C63923 @default.
- NCIT_C1359 type Class @default.
- NCIT_C1359 isDefinedBy ncit.owl @default.
- NCIT_C1359 label "Cyclopentenyl Cytosine" @default.
- NCIT_C1359 subClassOf NCIT_C1359 @default.
- NCIT_C1359 subClassOf NCIT_C1557 @default.
- NCIT_C1359 subClassOf NCIT_C186664 @default.
- NCIT_C1359 subClassOf NCIT_C1908 @default.
- NCIT_C1359 subClassOf NCIT_C1909 @default.
- NCIT_C1359 subClassOf NCIT_C2133 @default.
- NCIT_C1359 subClassOf NCIT_C272 @default.
- NCIT_C1359 subClassOf NCIT_C274 @default.
- NCIT_C1359 subClassOf NCIT_C471 @default.