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- NCIT_C1364 IAO_0000115 "A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties. (NCI04)" @default.
- NCIT_C1364 NCIT_NHC0 "C1364" @default.
- NCIT_C1364 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1364 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1364 NCIT_P108 "Didemnin B" @default.
- NCIT_C1364 NCIT_P175 "325319" @default.
- NCIT_C1364 NCIT_P175 "333841" @default.
- NCIT_C1364 NCIT_P207 "C0113768" @default.
- NCIT_C1364 NCIT_P210 "77327-05-0" @default.
- NCIT_C1364 NCIT_P319 "OR65D8FK1B" @default.
- NCIT_C1364 NCIT_P322 "FDA" @default.
- NCIT_C1364 NCIT_P329 "39974" @default.
- NCIT_C1364 NCIT_P330 "39974" @default.
- NCIT_C1364 NCIT_P366 "Didemnin_B" @default.
- NCIT_C1364 NCIT_P399 "39974" @default.
- NCIT_C1364 normalizedInformationContent "100" @default.
- NCIT_C1364 referenceCount "1" @default.
- NCIT_C1364 hasExactSynonym "15H-Pyrrolol[2,1-f][1,15,4,7,10,20]dioxatetraazacyclotri-cosine, Cyclic Peptide Deriv. (9CI)" @default.
- NCIT_C1364 hasExactSynonym "DIDEMNIN B" @default.
- NCIT_C1364 hasExactSynonym "Didemnin B" @default.
- NCIT_C1364 hasExactSynonym "Didemnin" @default.
- NCIT_C1364 hasExactSynonym "L-Tyrosine, N-[1-[N-[4-[[3-Hydroxy-4-[[N-[N-[1-(2-hydroxy-1-oxopropyl)- L-prolyl]-N-methyl-L-leucyl]-L-threonyl]amino]-5-methyl-1-oxoheptyl]oxy]-2,5-dimethyl-1,3-dioxohexyl]-L-leucyl]- L-prolyl]-N,O-dimethyl-, phi-lactone (9CI)" @default.
- NCIT_C1364 inSubset NCIT_C176424 @default.
- NCIT_C1364 inSubset NCIT_C63923 @default.
- NCIT_C1364 type Class @default.
- NCIT_C1364 isDefinedBy ncit.owl @default.
- NCIT_C1364 label "Didemnin B" @default.
- NCIT_C1364 subClassOf NCIT_C1364 @default.
- NCIT_C1364 subClassOf NCIT_C186664 @default.
- NCIT_C1364 subClassOf NCIT_C1908 @default.
- NCIT_C1364 subClassOf NCIT_C1909 @default.
- NCIT_C1364 subClassOf NCIT_C1976 @default.
- NCIT_C1364 subClassOf NCIT_C259 @default.
- NCIT_C1364 subClassOf NCIT_C274 @default.
- NCIT_C1364 subClassOf NCIT_C308 @default.
- NCIT_C1364 subClassOf NCIT_C574 @default.
- NCIT_C1364 subClassOf NCIT_C784 @default.