Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C136465> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- NCIT_C136465 IAO_0000115 "A monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed cell death 1 (PD-1, PCD-1; PDCD1) protein, with potential immune checkpoint inhibitory and antineoplastic activities. Upon administration, balstilimab binds to PD-1, and thereby blocks its binding to the PD-1 ligand programmed cell death-1 ligand 1 (PD-L1), and prevents the activation of its downstream signaling pathways. This may restore immune function through the activation of cytotoxic T-cells. PD-1, a transmembrane protein in the immunoglobulin superfamily expressed on activated T-cells, negatively regulates T-cell activation and effector function when activated by its ligand; it plays an important role in tumor evasion from host immunity." @default.
- NCIT_C136465 NCIT_A32 NCIT_C1909 @default.
- NCIT_C136465 NCIT_A7 NCIT_C94697 @default.
- NCIT_C136465 NCIT_NHC0 "C136465" @default.
- NCIT_C136465 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C136465 NCIT_P107 "Balstilimab" @default.
- NCIT_C136465 NCIT_P108 "Balstilimab" @default.
- NCIT_C136465 NCIT_P208 "CL523768" @default.
- NCIT_C136465 NCIT_P210 "2230167-06-1" @default.
- NCIT_C136465 NCIT_P319 "1Q2QT5M7EO" @default.
- NCIT_C136465 NCIT_P322 "CTRP" @default.
- NCIT_C136465 NCIT_P322 "FDA" @default.
- NCIT_C136465 NCIT_P322 "GDC" @default.
- NCIT_C136465 NCIT_P329 "789509" @default.
- NCIT_C136465 NCIT_P330 "789509" @default.
- NCIT_C136465 NCIT_P375 "Anti-PD1 Monoclonal Antibody AGEN2034" @default.
- NCIT_C136465 NCIT_P375 "Balstilimab" @default.
- NCIT_C136465 NCIT_P399 "789509" @default.
- NCIT_C136465 NCIT_R124 NCIT_C17710 @default.
- NCIT_C136465 NCIT_R124 NCIT_C17828 @default.
- NCIT_C136465 NCIT_R124 NCIT_C18219 @default.
- NCIT_C136465 NCIT_R124 NCIT_C19986 @default.
- NCIT_C136465 NCIT_R124 NCIT_C40474 @default.
- NCIT_C136465 normalizedInformationContent "100" @default.
- NCIT_C136465 referenceCount "1" @default.
- NCIT_C136465 hasExactSynonym "AGEN 2034" @default.
- NCIT_C136465 hasExactSynonym "AGEN-2034" @default.
- NCIT_C136465 hasExactSynonym "AGEN2034" @default.
- NCIT_C136465 hasExactSynonym "BALSTILIMAB" @default.
- NCIT_C136465 hasExactSynonym "Balstilimab" @default.
- NCIT_C136465 inSubset NCIT_C116977 @default.
- NCIT_C136465 inSubset NCIT_C116978 @default.
- NCIT_C136465 inSubset NCIT_C128784 @default.
- NCIT_C136465 inSubset NCIT_C157711 @default.
- NCIT_C136465 inSubset NCIT_C157712 @default.
- NCIT_C136465 inSubset NCIT_C176424 @default.
- NCIT_C136465 inSubset NCIT_C177537 @default.
- NCIT_C136465 inSubset NCIT_C63923 @default.
- NCIT_C136465 type Class @default.
- NCIT_C136465 isDefinedBy ncit.owl @default.
- NCIT_C136465 label "Balstilimab" @default.
- NCIT_C136465 subClassOf NCIT_C124946 @default.
- NCIT_C136465 subClassOf NCIT_C128037 @default.
- NCIT_C136465 subClassOf NCIT_C129821 @default.
- NCIT_C136465 subClassOf NCIT_C129822 @default.
- NCIT_C136465 subClassOf NCIT_C136465 @default.
- NCIT_C136465 subClassOf NCIT_C141144 @default.
- NCIT_C136465 subClassOf NCIT_C143250 @default.
- NCIT_C136465 subClassOf NCIT_C163758 @default.
- NCIT_C136465 subClassOf NCIT_C1908 @default.
- NCIT_C136465 subClassOf NCIT_C1909 @default.
- NCIT_C136465 subClassOf NCIT_C20401 @default.
- NCIT_C136465 subClassOf NCIT_C274 @default.
- NCIT_C136465 subClassOf NCIT_C307 @default.
- NCIT_C136465 subClassOf NCIT_C308 @default.