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- NCIT_C136986 IAO_0000115 "A preparation of cytotoxic T-lymphocytes (CTL) transfected with a chimeric antigen receptor (CAR) specifically recognizing the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1; LMP-1), with potential antineoplastic activity. Upon administration of the LMP1-specific CAR-expressing T lymphocytes to patients with LMP1-positive tumors, the CTLs specifically target and lyse tumor cells expressing LMP1, thereby inhibiting tumor cell proliferation. The tumor-associated antigen (TAA) LMP1 is expressed in various malignancies, including nasopharyngeal cancer and EBV-positive Hodgkin lymphoma." @default.
- NCIT_C136986 NCIT_NHC0 "C136986" @default.
- NCIT_C136986 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C136986 NCIT_P108 "LMP1-specific Chimeric Antigen Receptor-expressing T Lymphocytes" @default.
- NCIT_C136986 NCIT_P208 "CL524744" @default.
- NCIT_C136986 NCIT_P329 "789806" @default.
- NCIT_C136986 NCIT_P330 "789806" @default.
- NCIT_C136986 NCIT_P399 "789806" @default.
- NCIT_C136986 normalizedInformationContent "100" @default.
- NCIT_C136986 referenceCount "1" @default.
- NCIT_C136986 hasExactSynonym "Anti-LMP1 CAR T Cells" @default.
- NCIT_C136986 hasExactSynonym "LMP1-CAR-CTLs" @default.
- NCIT_C136986 hasExactSynonym "LMP1-CAR-T Cells" @default.
- NCIT_C136986 hasExactSynonym "LMP1-specific Chimeric Antigen Receptor-expressing T Lymphocytes" @default.
- NCIT_C136986 inSubset NCIT_C176424 @default.
- NCIT_C136986 type Class @default.
- NCIT_C136986 isDefinedBy ncit.owl @default.
- NCIT_C136986 label "LMP1-specific Chimeric Antigen Receptor-expressing T Lymphocytes" @default.
- NCIT_C136986 subClassOf NCIT_C129820 @default.
- NCIT_C136986 subClassOf NCIT_C129821 @default.
- NCIT_C136986 subClassOf NCIT_C129826 @default.
- NCIT_C136986 subClassOf NCIT_C136986 @default.
- NCIT_C136986 subClassOf NCIT_C137999 @default.
- NCIT_C136986 subClassOf NCIT_C142078 @default.
- NCIT_C136986 subClassOf NCIT_C154231 @default.
- NCIT_C136986 subClassOf NCIT_C1908 @default.
- NCIT_C136986 subClassOf NCIT_C1909 @default.
- NCIT_C136986 subClassOf NCIT_C1962 @default.
- NCIT_C136986 subClassOf NCIT_C274 @default.
- NCIT_C136986 subClassOf NCIT_C307 @default.
- NCIT_C136986 subClassOf NCIT_C308 @default.