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- NCIT_C13746 IAO_0000115 "The RING finger is a specialized type of Zn-finger consisting of 40 to 60 residues, which has the consensus sequence CX2CX(9-39)CX(1-3)HX(2-3)C/HX2CX(4-48)CX2C, that binds two atoms of zinc, and is involved in mediating protein-protein interactions. The RING domain mediates the interaction with the appropriate E2 enzyme. Unlike HECT E3 enzymes that form a thiol-ester with ubiquitin, RING fingers likely mediate ubiquitination by facilitating the direct transfer of ubiquitin from E2 enzyme to lysine residues on the target substrate." @default.
- NCIT_C13746 NCIT_NHC0 "C13746" @default.
- NCIT_C13746 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C13746 NCIT_P108 "Ring Finger Domain" @default.
- NCIT_C13746 NCIT_P207 "C1521759" @default.
- NCIT_C13746 NCIT_P366 "Ring_Finger_Domain" @default.
- NCIT_C13746 normalizedInformationContent "72.377402634338907" @default.
- NCIT_C13746 referenceCount "65" @default.
- NCIT_C13746 hasExactSynonym "Ring Finger Domain" @default.
- NCIT_C13746 hasExactSynonym "Ring Finger Motif" @default.
- NCIT_C13746 hasExactSynonym "Ring Finger" @default.
- NCIT_C13746 hasExactSynonym "Ring-Type Zinc Finger Domain" @default.
- NCIT_C13746 type Class @default.
- NCIT_C13746 isDefinedBy ncit.owl @default.
- NCIT_C13746 label "Ring Finger Domain" @default.
- NCIT_C13746 subClassOf NCIT_C12219 @default.
- NCIT_C13746 subClassOf NCIT_C13303 @default.
- NCIT_C13746 subClassOf NCIT_C13379 @default.
- NCIT_C13746 subClassOf NCIT_C13426 @default.
- NCIT_C13746 subClassOf NCIT_C13453 @default.
- NCIT_C13746 subClassOf NCIT_C13671 @default.
- NCIT_C13746 subClassOf NCIT_C13746 @default.
- NCIT_C13746 subClassOf NCIT_C14134 @default.
- NCIT_C13746 subClassOf NCIT_C21599 @default.