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- NCIT_C13806 IAO_0000115 "The major histocompatibility complex (MHC) molecules are made of 2 chains, alpha and beta. In class I, the alpha chain is composed of 3 extracellular domains, a transmembrane region and a cytoplasmic tail while the beta chain is of a single extracellular domain. In class II, both the alpha and the beta chains are composed of 2 extracellular domains, a transmembrane region and a cytoplasmic tail. The immunoglobulin (Ig) constant chain domains and a single extracellular domain in each type of MHC chains are homologous and approximately one hundred amino acids long, and include a conserved intra-domain disulfide bond. Members of the immunoglobulin superfamily are found in hundreds of proteins of different functions, e.g., antibodies, the giant muscle kinase titin and receptor tyrosine kinases. Immunoglobulin-like domains may be involved in protein-protein and protein-ligand interactions. (InterPro IPR007110)" @default.
- NCIT_C13806 NCIT_NHC0 "C13806" @default.
- NCIT_C13806 NCIT_P106 "Amino Acid Sequence" @default.
- NCIT_C13806 NCIT_P108 "Immunoglobulin Domain" @default.
- NCIT_C13806 NCIT_P207 "C1512665" @default.
- NCIT_C13806 NCIT_P366 "Immunoglobulin_Domain" @default.
- NCIT_C13806 normalizedInformationContent "64.219867713963822" @default.
- NCIT_C13806 referenceCount "223" @default.
- NCIT_C13806 hasExactSynonym "Immunoglobulin Domain" @default.
- NCIT_C13806 hasExactSynonym "Immunoglobulin-Like Domain" @default.
- NCIT_C13806 type Class @default.
- NCIT_C13806 isDefinedBy ncit.owl @default.
- NCIT_C13806 label "Immunoglobulin Domain" @default.
- NCIT_C13806 subClassOf NCIT_C12219 @default.
- NCIT_C13806 subClassOf NCIT_C13303 @default.
- NCIT_C13806 subClassOf NCIT_C13379 @default.
- NCIT_C13806 subClassOf NCIT_C13806 @default.
- NCIT_C13806 subClassOf NCIT_C14134 @default.
- NCIT_C13806 subClassOf NCIT_C21599 @default.