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- NCIT_C13809 IAO_0000115 "The nuclear lamina is a proteinaceous filamentous meshwork of lamin proteins interacting with integral proteins of the inner nuclear membrane, including emerin, and is thought to play a role in nuclear stability, chromatin structure, and gene expression. Lamins are highly conserved in evolution and members of the intermediate filament protein family. Mammalian lamins are classified into two major types, A and B, with two subspecies of each: lamins A and C for the A type and B1 and B2 for the B type. Lamins A and C arise from one gene by alternative splicing. Pre-lamin A contains a carboxyl CAAX box that can be modified by farnesylation. During mitosis, the lamina meshwork is reversibly disassembled in parallel with phosphorylation of the lamins." @default.
- NCIT_C13809 NCIT_NHC0 "C13809" @default.
- NCIT_C13809 NCIT_P106 "Cell Component" @default.
- NCIT_C13809 NCIT_P108 "Nuclear Lamina" @default.
- NCIT_C13809 NCIT_P207 "C1136039" @default.
- NCIT_C13809 NCIT_P366 "Nuclear_Lamina" @default.
- NCIT_C13809 NCIT_R82 NCIT_C12219 @default.
- NCIT_C13809 NCIT_R82 NCIT_C12508 @default.
- NCIT_C13809 NCIT_R82 NCIT_C13197 @default.
- NCIT_C13809 NCIT_R82 NCIT_C13226 @default.
- NCIT_C13809 NCIT_R82 NCIT_C13265 @default.
- NCIT_C13809 NCIT_R82 NCIT_C14070 @default.
- NCIT_C13809 NCIT_R82 NCIT_C14135 @default.
- NCIT_C13809 NCIT_R82 NCIT_C21599 @default.
- NCIT_C13809 NCIT_R82 NCIT_C32221 @default.
- NCIT_C13809 NCIT_R82 NCIT_C32876 @default.
- NCIT_C13809 NCIT_R82 NCIT_C34070 @default.
- NCIT_C13809 NCIT_R82 NCIT_C43596 @default.
- NCIT_C13809 normalizedInformationContent "87.123597049860606" @default.
- NCIT_C13809 referenceCount "7" @default.
- NCIT_C13809 hasExactSynonym "Nuclear Lamina" @default.
- NCIT_C13809 type Class @default.
- NCIT_C13809 isDefinedBy ncit.owl @default.
- NCIT_C13809 label "Nuclear Lamina" @default.
- NCIT_C13809 subClassOf B032390315560a563b6597338378277f2 @default.
- NCIT_C13809 subClassOf B1cc272407b74a8c33640252c21691641 @default.
- NCIT_C13809 subClassOf NCIT_C12219 @default.
- NCIT_C13809 subClassOf NCIT_C13809 @default.
- NCIT_C13809 subClassOf NCIT_C32221 @default.
- NCIT_C13809 subClassOf NCIT_C34070 @default.