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- NCIT_C1394 IAO_0000115 "A liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. Muramyl tripeptide phosphatidylethanolamine (MTP-PE), a derivative of the mycobacterial cell wall component MDP, activates both monocytes and macrophages. Activated macrophages secrete cytokines and induce the recruitment and activation of other immune cells, which may result in indirect tumoricidal effects. Liposomal encapsulation of MTP-PE prolongs its half-life and enhances tissue targeting." @default.
- NCIT_C1394 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1394 NCIT_NHC0 "C1394" @default.
- NCIT_C1394 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1394 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1394 NCIT_P107 "Mifamurtide" @default.
- NCIT_C1394 NCIT_P108 "Mifamurtide" @default.
- NCIT_C1394 NCIT_P175 "628280" @default.
- NCIT_C1394 NCIT_P207 "C0129341" @default.
- NCIT_C1394 NCIT_P210 "838853-48-8" @default.
- NCIT_C1394 NCIT_P319 "1LM890Q4FY" @default.
- NCIT_C1394 NCIT_P322 "CTRP" @default.
- NCIT_C1394 NCIT_P322 "FDA" @default.
- NCIT_C1394 NCIT_P322 "GDC" @default.
- NCIT_C1394 NCIT_P322 "PCDC" @default.
- NCIT_C1394 NCIT_P325 "A drug being studied in the treatment of young adults with bone cancer that has gotten worse or come back. L-MTP-PE activates certain types of white blood cells and helps the immune system kill cancer cells. It is a type of immunostimulant." @default.
- NCIT_C1394 NCIT_P329 "41541" @default.
- NCIT_C1394 NCIT_P330 "41541" @default.
- NCIT_C1394 NCIT_P350 "C59H108N6O19P.Na.H2O" @default.
- NCIT_C1394 NCIT_P366 "Muramyl_Tripeptide_Phosphatidylethanolamine" @default.
- NCIT_C1394 NCIT_P375 "Mifamurtide" @default.
- NCIT_C1394 NCIT_P399 "41541" @default.
- NCIT_C1394 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1394 NCIT_R124 NCIT_C17930 @default.
- NCIT_C1394 NCIT_R124 NCIT_C17937 @default.
- NCIT_C1394 NCIT_R124 NCIT_C18839 @default.
- NCIT_C1394 NCIT_R124 NCIT_C21124 @default.
- NCIT_C1394 NCIT_R124 NCIT_C45548 @default.
- NCIT_C1394 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1394 NCIT_R125 NCIT_C17937 @default.
- NCIT_C1394 NCIT_R125 NCIT_C18095 @default.
- NCIT_C1394 NCIT_R125 NCIT_C18839 @default.
- NCIT_C1394 NCIT_R125 NCIT_C19143 @default.
- NCIT_C1394 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1394 NCIT_R125 NCIT_C26280 @default.
- NCIT_C1394 NCIT_R125 NCIT_C40584 @default.
- NCIT_C1394 NCIT_R125 NCIT_C40839 @default.
- NCIT_C1394 NCIT_R125 NCIT_C40912 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12219 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12508 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12519 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12529 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12547 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12558 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12621 @default.
- NCIT_C1394 NCIT_R72 NCIT_C12657 @default.
- NCIT_C1394 NCIT_R72 NCIT_C21599 @default.
- NCIT_C1394 NCIT_R72 NCIT_C32725 @default.
- NCIT_C1394 normalizedInformationContent "88.143637090998837" @default.
- NCIT_C1394 referenceCount "6" @default.
- NCIT_C1394 hasExactSynonym "CGP 19835A Lipid" @default.
- NCIT_C1394 hasExactSynonym "Junovan" @default.
- NCIT_C1394 hasExactSynonym "L-Alaninamide, N-(N-acetylmuramoyl)-L-alanyl-D-alpha-glutaminyl-N-((7R)-4-hydroxy-4-oxido-10-oxo-7-((1-oxohexadecyl)oxy)-3,5,9-trioxa-4-phosphapentacos-1-yl)-, Monosodium Salt, Hydrate" @default.
- NCIT_C1394 hasExactSynonym "L-MTP-PE" @default.
- NCIT_C1394 hasExactSynonym "MEPACT" @default.
- NCIT_C1394 hasExactSynonym "MIFAMURTIDE" @default.
- NCIT_C1394 hasExactSynonym "MTP-PE Liposome" @default.
- NCIT_C1394 hasExactSynonym "Mepact" @default.
- NCIT_C1394 hasExactSynonym "Mifamurtide" @default.
- NCIT_C1394 hasExactSynonym "Muramyl Tripeptide Phosphatidylethanolamine Liposome" @default.
- NCIT_C1394 hasExactSynonym "MuramylNAc-Ala-isoGln-Lys-tripeptide-PE" @default.
- NCIT_C1394 hasExactSynonym "mifamurtide" @default.
- NCIT_C1394 hasExactSynonym "muramyl tripeptide phosphatidylethanolamine" @default.
- NCIT_C1394 inSubset NCIT_C116977 @default.
- NCIT_C1394 inSubset NCIT_C116978 @default.
- NCIT_C1394 inSubset NCIT_C128784 @default.
- NCIT_C1394 inSubset NCIT_C157711 @default.
- NCIT_C1394 inSubset NCIT_C157712 @default.
- NCIT_C1394 inSubset NCIT_C176424 @default.
- NCIT_C1394 inSubset NCIT_C177537 @default.
- NCIT_C1394 inSubset NCIT_C179478 @default.
- NCIT_C1394 inSubset NCIT_C179531 @default.
- NCIT_C1394 inSubset NCIT_C63923 @default.
- NCIT_C1394 type Class @default.
- NCIT_C1394 isDefinedBy ncit.owl @default.
- NCIT_C1394 label "Mifamurtide" @default.
- NCIT_C1394 subClassOf NCIT_C1394 @default.
- NCIT_C1394 subClassOf NCIT_C1908 @default.
- NCIT_C1394 subClassOf NCIT_C1909 @default.
- NCIT_C1394 subClassOf NCIT_C2139 @default.
- NCIT_C1394 subClassOf NCIT_C308 @default.
- NCIT_C1394 equivalentClass B1ef449b8bc63b59632674d82b3021639 @default.
- NCIT_C1394 equivalentClass Bea2ecbe7d2a74063c9a4370a3a16d045 @default.