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- NCIT_C13945 IAO_0000115 "The FHA (Forkhead-Associated) domain is a phosphopeptide recognition domain found in many regulatory proteins. It displays specificity for phosphothreonine-containing epitopes but will also recognize phosphotyrosine with relatively high affinity. It spans approximately 80-100 amino acid residues folded into an 11-stranded sandwich, which sometimes contain small helical insertions between the loops connecting the strands. To date, genes encoding FHA-containing proteins have been identified in eubacterial and eukaryotic but not aracheal genomes. The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins and metabolic enzymes which partake in many different cellular processes. DNA repair, signal transduction, vesicular transport and protein degradation are just a few examples." @default.
- NCIT_C13945 NCIT_NHC0 "C13945" @default.
- NCIT_C13945 NCIT_P106 "Amino Acid Sequence" @default.
- NCIT_C13945 NCIT_P108 "FHA Domain" @default.
- NCIT_C13945 NCIT_P207 "C1517093" @default.
- NCIT_C13945 NCIT_P366 "FHA_Domain" @default.
- NCIT_C13945 normalizedInformationContent "86.239998175184226" @default.
- NCIT_C13945 referenceCount "8" @default.
- NCIT_C13945 hasExactSynonym "FHA Domain" @default.
- NCIT_C13945 hasExactSynonym "Forkhead-Associated Domain" @default.
- NCIT_C13945 type Class @default.
- NCIT_C13945 isDefinedBy ncit.owl @default.
- NCIT_C13945 label "FHA Domain" @default.
- NCIT_C13945 subClassOf NCIT_C12219 @default.
- NCIT_C13945 subClassOf NCIT_C13303 @default.
- NCIT_C13945 subClassOf NCIT_C13379 @default.
- NCIT_C13945 subClassOf NCIT_C13945 @default.
- NCIT_C13945 subClassOf NCIT_C14134 @default.
- NCIT_C13945 subClassOf NCIT_C21599 @default.