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- NCIT_C1399 IAO_0000115 "A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity. (NCI04)" @default.
- NCIT_C1399 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1399 NCIT_A5 NCIT_C1400 @default.
- NCIT_C1399 NCIT_NHC0 "C1399" @default.
- NCIT_C1399 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1399 NCIT_P106 "Antibiotic" @default.
- NCIT_C1399 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1399 NCIT_P108 "Peplomycin" @default.
- NCIT_C1399 NCIT_P175 "276382" @default.
- NCIT_C1399 NCIT_P207 "C0135981" @default.
- NCIT_C1399 NCIT_P210 "68247-85-8" @default.
- NCIT_C1399 NCIT_P319 "56H9L80NIZ" @default.
- NCIT_C1399 NCIT_P322 "FDA" @default.
- NCIT_C1399 NCIT_P322 "GDC" @default.
- NCIT_C1399 NCIT_P329 "39552" @default.
- NCIT_C1399 NCIT_P330 "39552" @default.
- NCIT_C1399 NCIT_P350 "C61H88N18O21S2" @default.
- NCIT_C1399 NCIT_P366 "Peplomycin" @default.
- NCIT_C1399 NCIT_P375 "Peplomycin" @default.
- NCIT_C1399 NCIT_P399 "39552" @default.
- NCIT_C1399 normalizedInformationContent "100" @default.
- NCIT_C1399 referenceCount "1" @default.
- NCIT_C1399 hasExactSynonym "(S)-n1-[3-[(1-phenylethyl)amino]propyl]bleomycinamide" @default.
- NCIT_C1399 hasExactSynonym "PEP" @default.
- NCIT_C1399 hasExactSynonym "PEPLEOMYCIN" @default.
- NCIT_C1399 hasExactSynonym "PEPLOMYCIN" @default.
- NCIT_C1399 hasExactSynonym "Pepleomycin" @default.
- NCIT_C1399 hasExactSynonym "Peplomycin" @default.
- NCIT_C1399 hasExactSynonym "n1-[3[[(S)-alpha-methylbenzyl]amino]propyl]bleomycinamide" @default.
- NCIT_C1399 inSubset NCIT_C128784 @default.
- NCIT_C1399 inSubset NCIT_C157711 @default.
- NCIT_C1399 inSubset NCIT_C157712 @default.
- NCIT_C1399 inSubset NCIT_C176424 @default.
- NCIT_C1399 inSubset NCIT_C177537 @default.
- NCIT_C1399 inSubset NCIT_C63923 @default.
- NCIT_C1399 type Class @default.
- NCIT_C1399 isDefinedBy ncit.owl @default.
- NCIT_C1399 label "Peplomycin" @default.
- NCIT_C1399 subClassOf NCIT_C1399 @default.
- NCIT_C1399 subClassOf NCIT_C186664 @default.
- NCIT_C1399 subClassOf NCIT_C1908 @default.
- NCIT_C1399 subClassOf NCIT_C1909 @default.
- NCIT_C1399 subClassOf NCIT_C2311 @default.
- NCIT_C1399 subClassOf NCIT_C259 @default.
- NCIT_C1399 subClassOf NCIT_C274 @default.
- NCIT_C1399 subClassOf NCIT_C2842 @default.
- NCIT_C1399 subClassOf NCIT_C582 @default.