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- NCIT_C14092 IAO_0000115 "First identified in human hnRNPK protein, the conserved KH Domain of around 45-70 amino acids is present in a variety of nucleic acid-binding proteins. The domain may bind RNA in vivo. KH motifs are found in one or multiple copies, interspersed with RGG repeats, that may function cooperatively or, in single motif proteins, independently. KH domains can be separated into two groups: type-1 (beta-alpha-alpha-beta-beta-alpha) and type-2 (alpha-beta-beta-alpha-alpha-beta). The VIGXXGXXI sequence is preserved in the RNA binding motif between helix 1 and 2 (type-1) and helix 2 and 3 (type-2). The beta sheets are supported by alpha helixes. (NCI)" @default.
- NCIT_C14092 NCIT_NHC0 "C14092" @default.
- NCIT_C14092 NCIT_P106 "Amino Acid Sequence" @default.
- NCIT_C14092 NCIT_P108 "KH Domain" @default.
- NCIT_C14092 NCIT_P207 "C1517645" @default.
- NCIT_C14092 NCIT_P366 "KH_Domain" @default.
- NCIT_C14092 normalizedInformationContent "83.556969816060246" @default.
- NCIT_C14092 referenceCount "12" @default.
- NCIT_C14092 hasExactSynonym "K Homology Domain" @default.
- NCIT_C14092 hasExactSynonym "KH Domain" @default.
- NCIT_C14092 type Class @default.
- NCIT_C14092 isDefinedBy ncit.owl @default.
- NCIT_C14092 label "KH Domain" @default.
- NCIT_C14092 subClassOf NCIT_C12219 @default.
- NCIT_C14092 subClassOf NCIT_C13303 @default.
- NCIT_C14092 subClassOf NCIT_C13379 @default.
- NCIT_C14092 subClassOf NCIT_C13671 @default.
- NCIT_C14092 subClassOf NCIT_C13720 @default.
- NCIT_C14092 subClassOf NCIT_C14092 @default.
- NCIT_C14092 subClassOf NCIT_C14134 @default.
- NCIT_C14092 subClassOf NCIT_C21599 @default.