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- NCIT_C14505 IAO_0000115 "Originally disseminated by Detweiler and carried by Furth (1928-1936) and the Rockefeller Institute for subsequent generations. The AKR mouse has an albino coat (genotype a, B, c) and is highly susceptible to leukemias. The strain is viremic from birth in that all tissues express the AKV retrovirus and copies of the AKV genome are integrated in the mouse genome, which is associated with leukemia development. The AKR strain is also a source of the Thy1.1 thymocyte antigen, which is expressed on thymocyte, bone marrow and T cell progenitors and is used as a marker for a variety of stem cells. The strain has a low reproductive performance with small litter sizes at birth and weaning." @default.
- NCIT_C14505 NCIT_NHC0 "C14505" @default.
- NCIT_C14505 NCIT_P106 "Mammal" @default.
- NCIT_C14505 NCIT_P107 "AKR/J Mouse" @default.
- NCIT_C14505 NCIT_P108 "AKR/J Mouse" @default.
- NCIT_C14505 NCIT_P207 "C1515841" @default.
- NCIT_C14505 NCIT_P322 "CDISC" @default.
- NCIT_C14505 NCIT_P325 "Originally disseminated by Detweiler and carried by Furth (1928-1936) and the Rockefeller Institute for subsequent generations. The AKR mouse has an albino coat (genotype a, B, c) and is highly susceptible to leukemias. The strain is viremic from birth in that all tissues express the AKV retrovirus and copies of the AKV genome are integrated in the mouse genome, which is associated with leukemia development. The AKR strain is also a source of the Thy1.1 thymocyte antigen, which is expressed on thymocyte, bone marrow and T cell progenitors and is used as a marker for a variety of stem cells." @default.
- NCIT_C14505 NCIT_P332 "MGI:2159745" @default.
- NCIT_C14505 NCIT_P366 "AKR_J_Mouse" @default.
- NCIT_C14505 normalizedInformationContent "100" @default.
- NCIT_C14505 referenceCount "1" @default.
- NCIT_C14505 hasExactSynonym "AKR/J Mouse" @default.
- NCIT_C14505 hasExactSynonym "AKR/J" @default.
- NCIT_C14505 inSubset NCIT_C61410 @default.
- NCIT_C14505 inSubset NCIT_C77526 @default.
- NCIT_C14505 inSubset NCIT_C77530 @default.
- NCIT_C14505 type Class @default.
- NCIT_C14505 isDefinedBy ncit.owl @default.
- NCIT_C14505 label "AKR/J Mouse" @default.
- NCIT_C14505 subClassOf NCIT_C14182 @default.
- NCIT_C14505 subClassOf NCIT_C14234 @default.
- NCIT_C14505 subClassOf NCIT_C14238 @default.
- NCIT_C14505 subClassOf NCIT_C14246 @default.
- NCIT_C14505 subClassOf NCIT_C14250 @default.
- NCIT_C14505 subClassOf NCIT_C14270 @default.
- NCIT_C14505 subClassOf NCIT_C14282 @default.
- NCIT_C14505 subClassOf NCIT_C14420 @default.
- NCIT_C14505 subClassOf NCIT_C14421 @default.
- NCIT_C14505 subClassOf NCIT_C14505 @default.
- NCIT_C14505 subClassOf NCIT_C25796 @default.