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- NCIT_C146779 IAO_0000115 "A preparation of autologous T-lymphocytes that are genetically modified with a lentiviral vector encoding a T-cell receptor (TCR) specific for an as of yet not identified tumor-associated antigen (TAA), with potential antineoplastic activity. Upon intravenous administration back into the patient, the autologous TCR-engineered T-cells IMA201 specifically recognize and bind to the TAA on cancer cells, which induces a cytotoxic T-lymphocyte (CTL)-mediated immune response against the TAA-positive cancer cells." @default.
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- NCIT_C146779 hasExactSynonym "ACTengine IMA201" @default.
- NCIT_C146779 hasExactSynonym "Autologous T-cell Receptor-engineered T-cells IMA201" @default.
- NCIT_C146779 hasExactSynonym "Autologous TCR-engineered T-cells IMA201" @default.
- NCIT_C146779 hasExactSynonym "IMA 201" @default.
- NCIT_C146779 hasExactSynonym "IMA-201" @default.
- NCIT_C146779 hasExactSynonym "IMA201 Autologous T-lymphocytes" @default.
- NCIT_C146779 hasExactSynonym "IMA201 T-cells" @default.
- NCIT_C146779 hasExactSynonym "IMA201" @default.
- NCIT_C146779 inSubset NCIT_C116977 @default.
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- NCIT_C146779 type Class @default.
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- NCIT_C146779 label "Autologous TCR-engineered T-cells IMA201" @default.
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