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- NCIT_C146821 IAO_0000115 "A topical ointment composed of the water-insoluble taxane paclitaxel that has been processed to form uncoated nanoparticles, with potential antineoplastic activity. Upon topical administration of nanoparticle paclitaxel ointment SOR007 to the affected area, and following epithelial and dermal penetration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, which leads to the inhibition of cell division, thereby halting the proliferation of rapidly-dividing tumor cells. The nanoparticles in the nanoparticle paclitaxel ointment are produced through a specific proprietary submicron particle production." @default.
- NCIT_C146821 NCIT_A32 NCIT_C1909 @default.
- NCIT_C146821 NCIT_NHC0 "C146821" @default.
- NCIT_C146821 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C146821 NCIT_P107 "Nanoparticle Paclitaxel Ointment SOR007" @default.
- NCIT_C146821 NCIT_P108 "Nanoparticle Paclitaxel Ointment SOR007" @default.
- NCIT_C146821 NCIT_P208 "CL544868" @default.
- NCIT_C146821 NCIT_P322 "CTRP" @default.
- NCIT_C146821 NCIT_P322 "GDC" @default.
- NCIT_C146821 NCIT_P329 "792258" @default.
- NCIT_C146821 NCIT_P330 "792258" @default.
- NCIT_C146821 NCIT_P375 "Nanoparticle Paclitaxel Ointment SOR007" @default.
- NCIT_C146821 NCIT_P399 "792258" @default.
- NCIT_C146821 NCIT_R124 NCIT_C17828 @default.
- NCIT_C146821 NCIT_R124 NCIT_C20480 @default.
- NCIT_C146821 NCIT_R124 NCIT_C40795 @default.
- NCIT_C146821 NCIT_R124 NCIT_C40798 @default.
- NCIT_C146821 normalizedInformationContent "100" @default.
- NCIT_C146821 referenceCount "1" @default.
- NCIT_C146821 hasExactSynonym "NanoPac Ointment" @default.
- NCIT_C146821 hasExactSynonym "Nanopartcle Paclitaxel SOR007" @default.
- NCIT_C146821 hasExactSynonym "Nanoparticle Paclitaxel Ointment SOR007" @default.
- NCIT_C146821 hasExactSynonym "SOR007 Ointment" @default.
- NCIT_C146821 hasExactSynonym "SOR007" @default.
- NCIT_C146821 hasExactSynonym "Topical Nanoparticle Paclitaxel Ointment" @default.
- NCIT_C146821 hasExactSynonym "Uncoated Nanoparticle Paclitaxel Ointment" @default.
- NCIT_C146821 inSubset NCIT_C116977 @default.
- NCIT_C146821 inSubset NCIT_C116978 @default.
- NCIT_C146821 inSubset NCIT_C128784 @default.
- NCIT_C146821 inSubset NCIT_C157711 @default.
- NCIT_C146821 inSubset NCIT_C157712 @default.
- NCIT_C146821 inSubset NCIT_C176424 @default.
- NCIT_C146821 inSubset NCIT_C177537 @default.
- NCIT_C146821 type Class @default.
- NCIT_C146821 isDefinedBy ncit.owl @default.
- NCIT_C146821 label "Nanoparticle Paclitaxel Ointment SOR007" @default.
- NCIT_C146821 subClassOf NCIT_C146821 @default.
- NCIT_C146821 subClassOf NCIT_C186664 @default.
- NCIT_C146821 subClassOf NCIT_C1908 @default.
- NCIT_C146821 subClassOf NCIT_C1909 @default.
- NCIT_C146821 subClassOf NCIT_C25974 @default.
- NCIT_C146821 subClassOf NCIT_C273 @default.
- NCIT_C146821 subClassOf NCIT_C274 @default.
- NCIT_C146821 subClassOf NCIT_C61078 @default.
- NCIT_C146821 subClassOf NCIT_C67437 @default.