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- NCIT_C148142 IAO_0000115 "A cancer vaccine composed of a genetically engineered, replication-deficient adenovirus carrying the gene encoding human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon vaccination with the adenoviral-PSA vaccine ETBX-071, the adenovirus infects cells and expresses PSA. In turn, PSA activates the immune system and induces a cytotoxic T-lymphocyte (CTL) response against PSA-expressing tumor cells. PSA, a tumor associated antigen (TAA), is expressed by prostate epithelial cells and is overexpressed in prostate cancer." @default.
- NCIT_C148142 NCIT_A32 NCIT_C1909 @default.
- NCIT_C148142 NCIT_NHC0 "C148142" @default.
- NCIT_C148142 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C148142 NCIT_P106 "Virus" @default.
- NCIT_C148142 NCIT_P108 "Adenoviral PSA Vaccine ETBX-071" @default.
- NCIT_C148142 NCIT_P208 "CL550802" @default.
- NCIT_C148142 NCIT_P322 "GDC" @default.
- NCIT_C148142 NCIT_P329 "795436" @default.
- NCIT_C148142 NCIT_P330 "795436" @default.
- NCIT_C148142 NCIT_P375 "Adenoviral PSA Vaccine ETBX-071" @default.
- NCIT_C148142 NCIT_P399 "795436" @default.
- NCIT_C148142 normalizedInformationContent "100" @default.
- NCIT_C148142 referenceCount "1" @default.
- NCIT_C148142 hasExactSynonym "Adenoviral PSA Prostate Cancer Vaccine ETBX-071" @default.
- NCIT_C148142 hasExactSynonym "Adenoviral PSA Vaccine ETBX-071" @default.
- NCIT_C148142 hasExactSynonym "ETBX-071" @default.
- NCIT_C148142 inSubset NCIT_C157711 @default.
- NCIT_C148142 inSubset NCIT_C157712 @default.
- NCIT_C148142 inSubset NCIT_C176424 @default.
- NCIT_C148142 inSubset NCIT_C177537 @default.
- NCIT_C148142 type Class @default.
- NCIT_C148142 isDefinedBy ncit.owl @default.
- NCIT_C148142 label "Adenoviral PSA Vaccine ETBX-071" @default.
- NCIT_C148142 subClassOf NCIT_C129820 @default.
- NCIT_C148142 subClassOf NCIT_C148142 @default.
- NCIT_C148142 subClassOf NCIT_C1572 @default.
- NCIT_C148142 subClassOf NCIT_C1663 @default.
- NCIT_C148142 subClassOf NCIT_C1908 @default.
- NCIT_C148142 subClassOf NCIT_C1909 @default.
- NCIT_C148142 subClassOf NCIT_C274 @default.
- NCIT_C148142 subClassOf NCIT_C307 @default.
- NCIT_C148142 subClassOf NCIT_C308 @default.
- NCIT_C148142 subClassOf NCIT_C49146 @default.
- NCIT_C148142 subClassOf NCIT_C923 @default.
- NCIT_C148142 subClassOf NCIT_C96404 @default.